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Invitrogen
SLC28A2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 8
SLC28A2 Antibody (PA5-63151) in IHC
Immunohistochemical staining of SLC28A2 in human colon, liver, lymph node and small intestine using SLC28A2 Polyclonal Antibody (Product # PA5-63151) (A) shows similar protein distribution across tissues to an independent SLC28A2 Polyclonal Antibody (B).
Product Details
PA5-63151
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC28A2. Recombinant protein control fragment (Product #RP-103224).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647437
Product Specific Information
Immunogen sequence: GAEADCVSFP NTSFTNRTYE TYMCCRGLFQ STSLNGTNPP SFSGPWEDKE FSAMALTNCC GFYNNTVCA
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 74%.
Target Information
The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CNT 2; CNT-2; Concentrative nucleoside transporter 2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/nucleoside cotransporter 2; Sodium/purine nucleoside co-transporter; solute carrier family 28 (concentrative nucleoside transporter), member 2; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; Solute carrier family 28 member 2; SPNT
Gene Aliases: CNT2; HCNT2; HsT17153; SLC28A2; SPNT1
UniProt ID: (Human) O43868
Entrez Gene ID: (Human) 9153
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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