Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: PESPRWLIQK GQTQKARRIL SQMRGNQTID EEYDSIKNNI EEEEKEVGSA GPVICRMLSY P
SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; proton (H+) myo-inositol symporter; Proton myo-inositol cotransporter; solute carrier family 2 (facilitated glucose transporter), member 13; Solute carrier family 2 member 13
Gene Aliases: HMIT; SLC2A13
UniProt ID: (Human) Q96QE2
Entrez Gene ID: (Human) 114134
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