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SLC2A13 Antibody (PA5-97325) in WB
Western blot analysis of SLC2A13 in extracts of various cell lines. Samples were incubated with SLC2A13 Polyclonal antibody (Product # PA5-97325) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-97325
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 564-648 of human SLC2A13 (NP_4431173)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2809127
Product Specific Information
Immunogen sequence: LHTAEYLTYY GAFFLYAGFA AVGLLFIYGC LPETKGKKLE EIESLFDNRL CTCGTSDSDE GRYIEYIRVK GSNYHLSDND ASDVE; Positive Samples: HeLa, SH-SY5Y, HepG2, NCI-H460, HT-1080, K-562, Mouse kidney, Mouse pancreas, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
SLC2A13 (solute carrier family 2 (facilitated glucose transporter), member 13) is a 648 multi-pass membrane protein that belongs to the major facilitator superfamily and the sugar transporter family. SLC2A13 is a H+-myo-inositol cotransporter that can also transport related stereoisomers. Human SLC2A13 shares 90% identity with its rat homolog. The rat sequence has 12 transmembrane domains, 3 N-glycosylation sites, several motifs important for glucose transport activity, and an endoplasmic reticulum retention signal and dileucine internalization signal in the N-terminal region. SLC2A13 has been shown to specifically transport myoinositol but not hexoses, and decreasing the pH of the extracellular medium from 7.0 to 5.0 markedly increased transport activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H(+)-myo-inositol cotransporter; H(+)-myo-inositol symporter; hmit; proton (H+) myo-inositol symporter; Proton myo-inositol cotransporter; proton myo-inositol symporter; solute carrier family 2 (facilitated glucose transporter), member 13; Solute carrier family 2 member 13
Gene Aliases: 6530403A04; A630029G22Rik; AI505012; Gm308; HMIT; SLC2A13
UniProt ID: (Human) Q96QE2, (Rat) Q921A2, (Mouse) Q3UHK1
Entrez Gene ID: (Human) 114134, (Rat) 171147, (Mouse) 239606
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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