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SLC45A2 is a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka, 'B, ' encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4. The protein encoded by this gene encodes a melanocyte differentiation antigen that is expressed in a high percentage of melanoma cell lines. A similar sequence gene in medaka, 'B, ' encodes a transporter that mediates melanin synthesis. Mutations in this gene are a cause of oculocutaneous albinism type 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: Melanoma antigen AIM1; Membrane-associated transporter protein; Protein AIM-1; Solute carrier family 45 member 2; solute carrier family 45, member 2; underwhite
Gene Aliases: 1A1; AIM1; MATP; OCA4; SHEP5; SLC45A2
UniProt ID: (Human) Q9UMX9
Entrez Gene ID: (Human) 51151
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