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Immunogen sequence: ALISCLTGPT KRSTLAPGLL WWDLARQTAS VAPKEEVAIL DDNLVKGPEE LPTGNKKPPG FLPTNEDRLF FLGQKELEGA GSWTPCVGHD GGRDQQETNL; Positive Samples: Mouse testis; Cellular Location: Membrane, Multi-pass membrane protein
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Natrium iodide transporter; Sodium-iodide symporter; Sodium/iodide cotransporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; Solute carrier family 5 member 5; solute carrier family 5, member 5
Gene Aliases: NIS; SLC5A5; TDH1
UniProt ID: (Human) Q92911, (Rat) Q63008
Entrez Gene ID: (Human) 6528, (Rat) 114613, (Mouse) 114479
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