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Product Details
PA5-53045
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC6A1. Recombinant protein control fragment (Product #RP-102433).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647542
Product Specific Information
Immunogen sequence: IYYLYNSFTT TLPWKQCDNP WNTDRCFSNY SMVNTTNMTS AVVEFWERNM HQMTDGLDKP G
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
GAT-1 (SLC6A1) The protein encoded by SLC6A1 is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA T-1; GABA T1; GABA transporter 1; GABA transporter protein; GABAT1; gamma-aminobutyric acid (GABA-A) transporter 1; GAT-1; Sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter), member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
Gene Aliases: A730043E01; GABATHG; GABATR; Gabt; GABT1; GAT-1; GAT1; MAE; SLC6A1; XT-1; Xtrp1
UniProt ID: (Human) P30531, (Rat) P23978, (Mouse) P31648
Entrez Gene ID: (Human) 6529, (Rat) 79212, (Mouse) 232333
transport
neurotransmitter transport
chemical synaptic transmission
learning
response to toxic substance
response to sucrose
response to lead ion
positive regulation of gamma-aminobutyric acid secretion
response to purine-containing compound
gamma-aminobutyric acid transport
negative regulation of synaptic transmission, GABAergic
response to estradiol
response to cocaine
protein homooligomerization
response to calcium ion
gamma-aminobutyric acid import
transmembrane transport
mitophagy in response to mitochondrial depolarization
response to organic substance
response to organonitrogen compound
response to organic cyclic compound
amino acid transmembrane transport
sodium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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