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SLC6A1 Antibody (PA5-85766) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SLC6A1 was performed in DIV9 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: SLC6A1 Polyclonal Antibody (Product # PA5-85766) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-85766
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of mouse GABA Transporter 1.
Conjugate
Form
Liquid
Concentration
1.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792903
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Human (98%), Mouse (100%), Rat (100%), Xenopus laevis (85%), Rhesus Monkey (98%), Bovine (94%).
Positive Control: rat cerebellum.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GAT-1 (SLC6A1) The protein encoded by SLC6A1 is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA T-1; GABA T1; GABA transporter protein; GABAT1; gamma-aminobutyric acid (GABA-A) transporter 1; GAT-1; Sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
Gene Aliases: A730043E01; GABATHG; GABATR; Gabt; Gabt1; GAT-1; Gat1; Slc6a1; XT-1; Xtrp1
UniProt ID: (Rat) P23978, (Mouse) P31648
Entrez Gene ID: (Rat) 79212, (Mouse) 232333
neurotransmitter transport
learning
response to toxic substance
response to sucrose
response to organic substance
response to organonitrogen compound
response to lead ion
positive regulation of gamma-aminobutyric acid secretion
response to organic cyclic compound
response to purine-containing compound
negative regulation of synaptic transmission, GABAergic
response to estradiol
response to cocaine
protein homooligomerization
response to calcium ion
gamma-aminobutyric acid import
transmembrane transport
amino acid transmembrane transport
transport
sodium ion transmembrane transport
mitophagy in response to mitochondrial depolarization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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