Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-33053
Product Specifications
Species Reactivity
Dog,
Human,
Non-human primate,
Rabbit
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 14 amino acid peptide from N-terminus of human SLC7A5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550514
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Dog, Elephant, Rabbit, Platypus (100%); Opossum (93%); Mouse, Rat, Bat, Hamster, Panda, Chicken (86%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.It is sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.It involved in cellular amino acid uptake and the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta.Acts as an amino acid exchanger and plays a role in neuronal cell proliferation (neurogenesis) in brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 4F2; 4F2 LC; 4F2 light chain; 4F2HC; 4F2LC; 4T2HC; blood-brain barrier large neutral amino acid transporter light chain; CD98 light chain; CD98HC; E16; hLAT1; Integral membrane protein E16; L-type amino acid transporter 1; large neutral amino acids transporter 1; Large neutral amino acids transporter small subunit 1; LAT1; LAT1 light chain; light chain of LAT1 heterodimer; MDU1; MP hLAT1; NACAE; SLC7A5; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; Solute carrier family 7 member 5; y+ system cationic amino acid transporter
Gene Aliases: 4F2LC; CD98; CD98LC; D16S469E; E16; hLAT1; JHI-21; LAT1; MPE16; SLC7A5
UniProt ID: (Human) Q01650, (Rabbit) Q7YQK4
Entrez Gene ID: (Human) 8140, (Dog) 489667, (Rabbit) 100008844
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support