Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 5
SLIT3 Antibody (PA5-104142) in ICC/IF
Immunofluorescent analysis of SLIT3 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and SLIT3 polyclonal antibody (Product # PA5-104142) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-104142
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLIT3(Accession O75094), corresponding to amino acid residues K1260-R1310.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853470
Product Specific Information
Antibody detects endogenous levels of total SLIT3.
Target Information
SLIT3 may act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Multiple EGF-like domains protein 5; multiple epidermal growth factor-like domains 5; Multiple epidermal growth factor-like domains protein 5; SLIL2FLJ10764; slit homolog 3; Slit homolog 3 protein; Slit-3
Gene Aliases: b2b2362.1Clo; KIAA0814; MEGF5; SLIL2; Slit-3; SLIT1; slit2; SLIT3; UNQ691/PRO1336
UniProt ID: (Human) O75094, (Rat) O88280, (Mouse) Q9WVB4
Entrez Gene ID: (Human) 6586, (Rat) 83467, (Mouse) 20564
axon guidance
negative regulation of cell proliferation
organ morphogenesis
negative regulation of gene expression
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
negative regulation of cell growth
cellular response to hormone stimulus
Roundabout signaling pathway
axon extension involved in axon guidance
regulation of axonogenesis
negative chemotaxis
response to cortisol
apoptotic process involved in luteolysis
negative regulation of chemokine-mediated signaling pathway
brain development
spinal cord development
cell differentiation
multicellular organism development
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support