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Product Details
H00006586-M07
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1D11
Immunogen
SLIT3 (NP_003053, 1371 a.a. approximately 1470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: PCLGHRCHHG KCVATGTSYM CKCAEGYGGD LCDNKNDSAN ACSAFKCHHG QCHISDQGEP YCLCQPGFSG EHCQQENPCL GQVVREVIRR QKGYASCATA
Target Information
SLIT3 may act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Multiple EGF-like domains protein 5; Multiple epidermal growth factor-like domains protein 5; SLIL2FLJ10764; slit homolog 3; Slit homolog 3 protein; Slit-3
Gene Aliases: KIAA0814; MEGF5; SLIL2; Slit-3; SLIT1; slit2; SLIT3; UNQ691/PRO1336
UniProt ID: (Human) O75094
Entrez Gene ID: (Human) 6586
axon guidance
negative regulation of cell proliferation
organ morphogenesis
negative regulation of gene expression
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
negative regulation of cell growth
cellular response to hormone stimulus
Roundabout signaling pathway
axon extension involved in axon guidance
regulation of axonogenesis
negative chemotaxis
response to cortisol
apoptotic process involved in luteolysis
negative regulation of chemokine-mediated signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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