Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
SMARCA5 Recombinant Rabbit Monoclonal Antibody (23GB4160)
FIGURE: 1 / 3
SMARCA5 Antibody (MA5-52664) in ICC/IF
Immunocytochemistry analysis of SMARCA5 in C2C12 cells. Nuclei were stained blue with DAPI; SMARCA5 recombinant monoclonal antibody (Product # MA5-52664) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-52664
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB4160
Immunogen
A synthesized peptide derived from SNF2H (1000-1052AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: hSNF2H; mSnf2h; Sucrose nonfermenting protein 2 homolog; sucrose nonfermenting-like 5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
Gene Aliases: 4933427E24Rik; D030040M08Rik; D330027N15Rik; hISWI; hSNF2H; ISWI; MommeD4; SMARCA5; SNF2H; WCRF135
UniProt ID: (Human) O60264, (Mouse) Q91ZW3
Entrez Gene ID: (Human) 8467, (Rat) 307766, (Mouse) 93762
DNA binding
helicase activity
protein binding
ATP binding
ATPase activity
nucleosome binding
histone binding
molecular_function
nucleotide binding
nucleic acid binding
chromatin binding
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
DNA helicase
chromatin silencing at rDNA
double-strand break repair
nucleosome assembly
chromatin remodeling
DNA-templated transcription, initiation
regulation of transcription from RNA polymerase II promoter
covalent chromatin modification
nucleosome positioning
CENP-A containing nucleosome assembly
ATP-dependent chromatin remodeling
positive regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
chromatin assembly or disassembly
biological_process
metabolic process
embryo development
chromatin modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support