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Product Details
PA1-4695
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the C-terminal region of rat SNAP25 conjugated to KLH
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2192048
Product Specific Information
This antibody is predicted to react with mouse, human, zebrafish, bovine, canine, chicken, guinea pig and non-human primate based on 100% sequence homology.
In Western blot, this antibody is specific for the ~25 kDa SNAP25 protein.
Target Information
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALMS1; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; FLJ23079; HGNC:11132; SNAP 25; SNAP-25; snp25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25 kDa
Gene Aliases: Snap; SNAP-25a; SNAP-25B; Snap25
UniProt ID: (Rat) P60881
Entrez Gene ID: (Rat) 25012
exocytosis
neurotransmitter secretion
axonogenesis
long-term memory
regulation of neuron projection development
synaptic vesicle priming
endosomal transport
growth hormone secretion
sleep
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of insulin secretion
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
regulation of synapse assembly
long-term synaptic potentiation
regulation of establishment of protein localization
potassium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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