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Invitrogen
SNAP25 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
SNAP25 Antibody (PA5-19701) in ICC/IF
Immunofluorescence analysis of Synaptosomal-associated protein 25 was performed using 70% confluent log phase PC-12 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with SNAP25 Polyclonal Antibody (Product # PA5-19701) at 0.8 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Recombinant Secondary Antibody, A... View More
Product Details
PA5-19701
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human SNAP25.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10986997
Product Specific Information
This antibody is predicted to react with chicken and cow based on sequence homology.
Store antibody at 4ºC for 1-2 weeks. For long-term storage, store at -20ºC.
Target Information
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALMS1; blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; etID17571.20; etID69167.20; FLJ23079; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; SNAP-25.1; SNAP-25A; Snap25.1; snp25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; Synaptosomal-associated protein 25-A; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25a; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa; Synaptosome-associated protein 25.1
Gene Aliases: bA416N4.2; Bdr; CMS18; dJ1068F16.2; fj42b02; fj45g04; fj48c02; GENA70; RIC-4; RIC4; SEC9; si:dkeyp-8f4.6; SNAP; SNAP-25; SNAP-25a; SNAP-25B; SNAP25; snap25.1; snap25a; sp; SUP; wu:fj42b02; wu:fj45g04; wu:fj48c02
UniProt ID: (Human) P60880, (Rat) P60881, (Mouse) P60879, (Zebrafish) Q5TZ66
Entrez Gene ID: (Human) 6616, (Rat) 25012, (Mouse) 20614, (Zebrafish) 30712
neurotransmitter uptake
chemical synaptic transmission
neurotransmitter secretion
locomotory behavior
associative learning
regulation of neuron projection development
glutamate secretion
synaptic vesicle exocytosis
synaptic vesicle docking
synaptic vesicle priming
synaptic vesicle fusion to presynaptic active zone membrane
regulation of insulin secretion
long-term synaptic potentiation
exocytosis
axonogenesis
long-term memory
endosomal transport
growth hormone secretion
sleep
positive regulation of insulin secretion
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
regulation of synapse assembly
regulation of establishment of protein localization
potassium ion transmembrane transport
regulation of ion transmembrane transport
mitotic cytokinesis
vesicle fusion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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