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Invitrogen
SNAP25 Monoclonal Antibody (S-7B8)
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
SNAP25 Antibody (MA1-12710) in ICC/IF
Immunofluorescence analysis of Synaptosomal-associated protein 25 was performed using 70% confluent log phase PC-12 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with SNAP25 Monoclonal Antibody (S-7B8) (Product # MA1-12710) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Recombinant Secondary Antibod... View More
Product Details
MA1-12710
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Chicken,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
S-7B8
Immunogen
Rat brain synaptosomal membranes and mouse NS1 Cells.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1087381
Product Specific Information
A suggested positive control for this product is cerebellum tissue lysate.
Target Information
SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALMS1; blind drunk; CG17676; CG17884; CG40452; Dmel CG40452; Dmel_CG40452; FLJ23079; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; SNAP 25; SNAP-25; snp25; SUP; Super protein; Synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25kDa
Gene Aliases: bA416N4.2; Bdr; CMS18; dJ1068F16.2; GENA70; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SNAP-25a; SNAP-25B; SNAP25; sp; SUP
UniProt ID: (Human) P60880, (Bovine) Q17QQ3, (Rat) P60881, (Mouse) P60879
Entrez Gene ID: (Chicken) 396444, (Human) 6616, (Bovine) 540853, (Rat) 25012, (Mouse) 20614
exocytosis
vesicle fusion
locomotory behavior
associative learning
regulation of neuron projection development
synaptic vesicle priming
synaptic vesicle fusion to presynaptic active zone membrane
long-term synaptic potentiation
regulation of establishment of protein localization
potassium ion transmembrane transport
exocytic insertion of neurotransmitter receptor to postsynaptic membrane
neurotransmitter receptor internalization
neurotransmitter uptake
chemical synaptic transmission
neurotransmitter secretion
glutamate secretion
synaptic vesicle exocytosis
synaptic vesicle docking
regulation of insulin secretion
axonogenesis
long-term memory
endosomal transport
growth hormone secretion
sleep
positive regulation of insulin secretion
positive regulation of hormone secretion
calcium ion-regulated exocytosis of neurotransmitter
regulation of synapse assembly
regulation of ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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