Proteintech

SNAP29 Polyclonal Antibody

SNAP29 Antibody in Immunocytochemistry (ICC/IF)

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SNAP29 Antibody (12704-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HEK-293 cells using (Product # 12704-1-AP) (SNAP29 antibody), at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

SNAP29 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SNAP29 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12704-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 20 publications 20 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SNAP29 Fusion Protein Ag3382 (1-258 aa encoded by BC009715)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSAYPKSYN PFDDDGEDEG ARPAPWRDAR DLPDGPDAPA DRQQYLRQEV LRRAEATAAS TSRSLALMYE SEKVGVASSE ELARQRGVLE RTEKMVDKMD QDLKISQKHI NSIKSVFGGL VNYFKSKPVE TPPEQNGTLT SQPNNRLKEA ISTSKEQEAK YQASHPNLRK LDDTDPVPRG AGSAMSTDAY PKNPHLRAYH QKIDSNLDEL SMGLGRLKDI ALGMQTEIEE QDDILDRLTT KVDKLDVNIK STERKVRQL (1-258 aa encoded by BC009715 )

Target Information

SNAP29 encodes a product that is a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.

Hepatology (Baltimore, Md.)

Liu X,Tan S,Liu H,Jiang J,Wang X,Li L,Wu B

Sat Apr 01 00:00:00 EDT 2023

Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.

Hepatology (Baltimore, Md.)

Liu X,Tan S,Liu H,Jiang J,Wang X,Li L,Wu B

Sat Apr 01 00:00:00 EDT 2023

SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.

Autophagy

Zheng W,Chen Q,Liu H,Zeng L,Zhou Y,Liu X,Bai Y,Zhang J,Pan Y,Shao C

Wed Mar 01 00:00:00 EST 2023

Doxorubicin induces cardiomyocyte death owing to the accumulation of dysfunctional mitochondria by inhibiting the autophagy fusion process.

Free radical biology & medicine

Toda N,Sato T,Muraoka M,Lin D,Saito M,Li G,Song QC,Yanagisawa T,Yamauchi M

Wed Feb 01 00:00:00 EST 2023

The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication.

Autophagy

Hou P,Wang X,Wang H,Wang T,Yu Z,Xu C,Zhao Y,Wang W,Zhao Y,Chu F,Chang H,Zhu H,Lu J,Zhang F,Liang X,Li X,Wang S,Gao Y,He H

Wed Feb 01 00:00:00 EST 2023

NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8.

Science advances

Anandhan A,Dodson M,Shakya A,Chen J,Liu P,Wei Y,Tan H,Wang Q,Jiang Z,Yang K,Garcia JG,Chambers SK,Chapman E,Ooi A,Yang-Hartwich Y,Stockwell BR,Zhang DD

Fri Feb 03 00:00:00 EST 2023

Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.

Journal of periodontal research

Zhang T,Yang K,Chen Y,Jiang Y,Zhou Z,Liu J,Du Y,Wang L,Han X,Wu X,Wang X

Wed Feb 01 00:00:00 EST 2023

Neuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation.

iScience

Huang M,Bin NR,Rai J,Ma K,Chow CH,Eide S,Harada H,Xiao J,Feng D,Sun HS,Feng ZP,Gaisano HY,Pessin JE,Monnier PP,Okamoto K,Zhang L,Sugita S

Fri May 19 00:00:00 EDT 2023

TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.

Journal of hazardous materials

Tang H,Huang H,Wang D,Li P,Tian Z,Li D,Wang S,Ma R,Xia T,Wang A

Sun May 15 00:00:00 EDT 2022

TFEB ameliorates autophagy flux disturbance induced by PBDE-47 via up-regulating autophagy-lysosome fusion.

Journal of hazardous materials

Tang H,Huang H,Wang D,Li P,Tian Z,Li D,Wang S,Ma R,Xia T,Wang A

Sun May 15 00:00:00 EDT 2022

CHML is an NRF2 target gene that regulates mTOR function.

Molecular oncology

Dodson M,Dai W,Anandhan A,Schmidlin CJ,Liu P,Wilson NC,Wei Y,Kitamura N,Galligan JJ,Ooi A,Chapman E,Zhang DD

Fri Apr 01 00:00:00 EDT 2022

Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice.

Nature communications

Li T,Lu D,Yao C,Li T,Dong H,Li Z,Xu G,Chen J,Zhang H,Yi X,Zhu H,Liu G,Wen K,Zhao H,Gao J,Zhang Y,Han Q,Li T,Zhang W,Zhao J,Li T,Bai Z,Song M,He X,Zhou T,Xia Q,Li A,Pan X

Thu Feb 17 00:00:00 EST 2022

Weakened interaction of ATG14 and the SNARE complex blocks autophagosome-lysosome fusion contributes to fluoride-induced developmental neurotoxicity.

Ecotoxicology and environmental safety

Zhang Y,Han X,Tang Y,Zhang J,Hu Z,Xu W,Yao P,Niu Q

Sat Jan 15 00:00:00 EST 2022

Decreased neuronal synaptosome associated protein 29 contributes to poststroke cognitive impairment by disrupting presynaptic maintenance.

Theranostics

Yan W,Fan J,Zhang X,Song H,Wan R,Wang W,Yin Y

Mon Aug 16 00:00:00 EDT 2021

Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.

Cell death & disease

Zhao T,Zheng T,Yu H,Hu BH,Hu B,Ma P,Yang Y,Yang N,Hu J,Cao T,Chen G,Yan B,Peshoff M,Hatzoglou M,Geng R,Li B,Zheng QY

Mon Jan 04 00:00:00 EST 2021

DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function.

Cell death & disease

Cao Y,Li R,Shen M,Li C,Zou Y,Jiang Q,Liu S,Lu C,Li H,Liu H,Cai Y

Tue Apr 20 00:00:00 EDT 2021

Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.

Biochemical and biophysical research communications

Liu A,Wang W,Lu Z,Liu Z,Zhou W,Zhong Z,Ye Q

Fri Apr 23 00:00:00 EDT 2021

Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.

Biochemical and biophysical research communications

Liu A,Wang W,Lu Z,Liu Z,Zhou W,Zhong Z,Ye Q

Fri Apr 23 00:00:00 EDT 2021

Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells.

Stem cell research & therapy

Li Z,Liu S,Fu T,Peng Y,Zhang J

Wed Nov 27 00:00:00 EST 2019

KRAS regulation by small non-coding RNAs and SNARE proteins.

Nature communications

Che Y,Siprashvili Z,Kovalski JR,Jiang T,Wozniak G,Elcavage L,Khavari PA

Mon Nov 11 00:00:00 EST 2019

KRAS regulation by small non-coding RNAs and SNARE proteins.

Nature communications

Che Y,Siprashvili Z,Kovalski JR,Jiang T,Wozniak G,Elcavage L,Khavari PA

Mon Nov 11 00:00:00 EST 2019

The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses.

Cell reports

Wang K,Ma H,Liu H,Ye W,Li Z,Cheng L,Zhang L,Lei Y,Shen L,Zhang F

Tue May 14 00:00:00 EDT 2019

Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.

Biochimica et biophysica acta. Proteins and proteomics

Zeng HL,Yu FL,Zhang Z,Yang Q,Jin S,He X,Chen X,Shen Y,Cheng L,Guo L,Xu F

Thu Feb 01 00:00:00 EST 2018

Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.

Biochimica et biophysica acta. Proteins and proteomics

Zeng HL,Yu FL,Zhang Z,Yang Q,Jin S,He X,Chen X,Shen Y,Cheng L,Guo L,Xu F

Thu Feb 01 00:00:00 EST 2018

Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3.

Journal of lipid research

Kimura H,Arasaki K,Ohsaki Y,Fujimoto T,Ohtomo T,Yamada J,Tagaya M

Tue May 01 00:00:00 EDT 2018

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.

Nature cell biology

Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ

Wed Apr 01 00:00:00 EDT 2015

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.

Nature cell biology

Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ

Wed Apr 01 00:00:00 EDT 2015

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.

Nature cell biology

Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ

Sun Mar 01 00:00:00 EST 2015

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.

Nature cell biology

Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ

Sun Mar 01 00:00:00 EST 2015

Bioinformatics

Protein Aliases: FLJ21051; Golgi SNARE of 32 kDa; Gs32; SNAP-29; Soluble 29 kDa NSF attachment protein; Synaptosomal-associated protein 29; synaptosomal-associated protein 29kD; synaptosomal-associated protein, 29kD; synaptosomal-associated protein, 29kDa; synaptosome associated protein 29kDa; Vesicle-membrane fusion protein SNAP-29

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Gene Aliases: 1300018G05Rik; AI891940; AU020222; BB131856; CEDNIK; Gs32; SNAP-29; SNAP29

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UniProt ID: (Human) O95721, (Mouse) Q9ERB0

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Entrez Gene ID: (Human) 9342, (Rat) 116500, (Mouse) 67474

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Function(s)

SNAP receptor activity protein binding syntaxin binding SNARE protein

Process(es)

exocytosis vesicle targeting protein transport synaptic vesicle priming synaptic vesicle fusion to presynaptic active zone membrane cilium assembly membrane fusion autophagosome maturation transport autophagy

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SNAP29 Polyclonal Antibody

SNAP29 Antibody (12704-1-AP) in ICC/IF

Product Details

12704-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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