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Product Details
14316-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SOD3 Fusion Protein Ag5556 (1-240 aa encoded by BC014418)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLALLCSCL LLAAGASDAW TGEDSAEPNS DSAEWIRDMY AKVTEIWQEV MQRRDDDGTL HAACQVQPSA TLDAAQPRVT GVVLFRQLAP RAKLDAFFAL EGFPTEPNSS SRAIHVHQFG DLSQGCESTG PHYNPLAVPH PQHPGDFGNF AVRDGSLWRY RAGLAASLAG PHSIVGRAVV VHAGEDDLGR GGNQASVENG NAGRRLACCV VGVCGPGLWE RQAREHSERK KRRRESECKA A (1-240 aa encoded by BC014418)
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ALS1; EC SOD; EC-SOD; Extracellular superoxide dismutase [Cu-Zn]; MGC20077; SOD 3; superoxide dismutase; testicular tissue protein Li 175
Gene Aliases: EC-SOD; SOD3
UniProt ID: (Human) P08294
Entrez Gene ID: (Human) 6649
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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