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Product Details
PA5-110412
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOX11 (NP_0030991)
Conjugate
Form
Liquid
Concentration
1.71 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855823
Product Specific Information
Immunogen sequence: MVQQAESLEA ESNLPREALD TEEGEFMACS PVALDESDPD WCKTASGHIK RPMNAFMVWS KIERRKIMEQ SPDMHNAEIS KRLGKRWKML KDSEKIPFIR
Target Information
This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SRY; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-related HMG-box gene 11; Transcription factor SOX-11
Gene Aliases: 1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox-11; SOX11
UniProt ID: (Human) P35716, (Mouse) Q7M6Y2, (Rat) P0C1G9
Entrez Gene ID: (Human) 6664, (Mouse) 20666, (Rat) 84046
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
enhancer sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
translation factor activity, RNA binding
DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
HMG box transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
neural tube formation
lens morphogenesis in camera-type eye
outflow tract morphogenesis
cardiac ventricle formation
noradrenergic neuron differentiation
transcription from RNA polymerase II promoter
translation
positive regulation of cell proliferation
positive regulation of gene expression
negative regulation of gene expression
oligodendrocyte development
glial cell proliferation
neural crest cell development
regulation of transforming growth factor beta receptor signaling pathway
spinal cord development
glial cell development
neuron differentiation
positive regulation of BMP signaling pathway
positive regulation of hippo signaling
skeletal muscle cell differentiation
positive regulation of neuron differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
sympathetic nervous system development
embryonic digestive tract morphogenesis
embryonic skeletal system morphogenesis
negative regulation of lymphocyte proliferation
positive regulation of neurogenesis
hard palate development
soft palate development
limb bud formation
negative regulation of glial cell proliferation
ventricular septum morphogenesis
lung morphogenesis
negative regulation of cell death
neuroepithelial cell differentiation
eyelid development in camera-type eye
somite development
cornea development in camera-type eye
closure of optic fissure
signal transduction involved in cell cycle checkpoint
positive regulation of stem cell proliferation
negative regulation of transcription regulatory region DNA binding
positive regulation of lens epithelial cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
nervous system development
cell differentiation
cell proliferation
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