Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-37891
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-SRLYYSFKNITKQHP, from the internal region of SOX11 (aa309-323)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2554499
Product Specific Information
This antibody is predicted to react with mouse, rat, pig and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: SRY; SRY (sex-determining region Y)-box 11; SRY-related HMG-box gene 11; Transcription factor SOX-11
Gene Aliases: MRD27; SOX11
UniProt ID: (Human) P35716
Entrez Gene ID: (Human) 6664
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
enhancer sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
translation factor activity, RNA binding
HMG box transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
neural tube formation
lens morphogenesis in camera-type eye
outflow tract morphogenesis
cardiac ventricle formation
noradrenergic neuron differentiation
transcription from RNA polymerase II promoter
translation
positive regulation of cell proliferation
positive regulation of gene expression
negative regulation of gene expression
oligodendrocyte development
glial cell proliferation
neural crest cell development
regulation of transforming growth factor beta receptor signaling pathway
spinal cord development
glial cell development
neuron differentiation
positive regulation of BMP signaling pathway
positive regulation of hippo signaling
skeletal muscle cell differentiation
positive regulation of neuron differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
sympathetic nervous system development
embryonic digestive tract morphogenesis
embryonic skeletal system morphogenesis
negative regulation of lymphocyte proliferation
positive regulation of neurogenesis
hard palate development
soft palate development
limb bud formation
negative regulation of glial cell proliferation
ventricular septum morphogenesis
lung morphogenesis
negative regulation of cell death
neuroepithelial cell differentiation
eyelid development in camera-type eye
somite development
cornea development in camera-type eye
closure of optic fissure
signal transduction involved in cell cycle checkpoint
positive regulation of stem cell proliferation
negative regulation of transcription regulatory region DNA binding
positive regulation of lens epithelial cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support