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Invitrogen
SOX11 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
SOX11 Antibody (PA5-40698) in ICC/IF
Immunofluorescence analysis of SOX11 was performed using 70% confluent log phase SHSY-5Y and BeWo cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with SOX11 Polyclonal Antibody (Product # PA5-40698) at 5 µg/mL 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Recombinant Secondary Antibody, Alexa Fluor® 488 conjugate (P... View More
Product Details
PA5-40698
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human SOX11
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2608886
Product Specific Information
Peptide sequence: MVQQAESLEA ESNLPREALD TEEGEFMACS PVALDESDPD WCKTASGHIK
Sequence homology: Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%
Target Information
This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SRY; SRY (sex-determining region Y)-box 11; SRY-related HMG-box gene 11; Transcription factor SOX-11
Gene Aliases: MRD27; SOX11
UniProt ID: (Human) P35716
Entrez Gene ID: (Human) 6664
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
enhancer sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
translation factor activity, RNA binding
HMG box transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
neural tube formation
lens morphogenesis in camera-type eye
outflow tract morphogenesis
cardiac ventricle formation
noradrenergic neuron differentiation
transcription from RNA polymerase II promoter
translation
positive regulation of cell proliferation
positive regulation of gene expression
negative regulation of gene expression
oligodendrocyte development
glial cell proliferation
neural crest cell development
regulation of transforming growth factor beta receptor signaling pathway
spinal cord development
glial cell development
neuron differentiation
positive regulation of BMP signaling pathway
positive regulation of hippo signaling
skeletal muscle cell differentiation
positive regulation of neuron differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
sympathetic nervous system development
embryonic digestive tract morphogenesis
embryonic skeletal system morphogenesis
negative regulation of lymphocyte proliferation
positive regulation of neurogenesis
hard palate development
soft palate development
limb bud formation
negative regulation of glial cell proliferation
ventricular septum morphogenesis
lung morphogenesis
negative regulation of cell death
neuroepithelial cell differentiation
eyelid development in camera-type eye
somite development
cornea development in camera-type eye
closure of optic fissure
signal transduction involved in cell cycle checkpoint
positive regulation of stem cell proliferation
negative regulation of transcription regulatory region DNA binding
positive regulation of lens epithelial cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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