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SPON2 Polyclonal Antibody

View all (10) SPON2 antibodies

Questions & Answers

Questions & Answers

Antibody Testing Data (11)

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 11

SPON2 Antibody (20513-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using (Product # 20513-1-AP) (SPON2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SPON2 Antibody in Western Blot (WB)

Product Image Gallery

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using (Product # 20513-1-AP) (SPON2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue slide using (Product # 20513-1-AP) SPON2 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate hyperplasia using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 40x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate hyperplasia using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 10x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate cancer using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 40x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate cancer using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 10x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate cancer using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 40x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate cancer using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 10x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate cancer using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 40x lens).

SPON2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human prostate cancer using 20513-1-AP (SPON2 antibody) at dilution of 1:50 (under 10x lens).

SPON2 Antibody in Western Blot (WB) — LNCaP cells were subjected to SDS PAGE followed by western blot with 20513-1-AP (SPON2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Product Details

20513-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SPON2 Fusion Protein Ag14337 (32-221 aa encoded by BC002707)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.41 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: ESICSARAP AKYSITFTGK WSQTAFPKQY PLFRPPAQWS SLLGAAHSSD YSMWRKNQYV SNGLRDFAER GEAWALMKEI EAAGEALQSV HEVFSAPAVP SGTGQTSAEL EVQRRHSLVS FVVRIVPSPD WFVGVDSLDL CDGDRWREQA ALDLYPYDAG TDSGFTFSSP NFATIPQDTV TEITSSSPSH P (32-221 aa encoded by BC002707)

Target Information

Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Knockdown of SPON2 inhibits the growth of triple-negative breast cancer.

Frontiers in oncology

Hu X,Su C,Wei J

Sat Mar 25 00:00:00 EDT 2023

Integrative Analysis of DNA Methylation and Transcriptome Identifies a Predictive Epigenetic Signature Associated With Immune Infiltration in Gliomas.

Frontiers in cell and developmental biology

Zhang J,Yin J,Luo L,Huang D,Zhai D,Wang G,Xu N,Yang M,Song Y,Zheng G,Zhang Q

Sat Jun 19 00:00:00 EDT 2021

Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis.

Frontiers in cell and developmental biology

Li N,Liu S,Zhang Y,Yu L,Hu Y,Wu T,Fang M,Xu Y

Mon Mar 01 00:00:00 EST 2021

Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis.

Frontiers in cell and developmental biology

Li N,Liu S,Zhang Y,Yu L,Hu Y,Wu T,Fang M,Xu Y

Mon Mar 01 00:00:00 EST 2021

Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis.

Frontiers in cell and developmental biology

Li N,Liu S,Zhang Y,Yu L,Hu Y,Wu T,Fang M,Xu Y

Mon Mar 01 00:00:00 EST 2021

Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis.

Frontiers in cell and developmental biology

Li N,Liu S,Zhang Y,Yu L,Hu Y,Wu T,Fang M,Xu Y

Mon Mar 01 00:00:00 EST 2021

Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.

Journal of cellular and molecular medicine

Lu H,Feng Y,Hu Y,Guo Y,Liu Y,Mao Q,Xue W

Wed Jan 01 00:00:00 EST 2020

Bioinformatics

Protein Aliases: Differentially expressed in cancerous and non-cancerous lung cells 1; DIL-1; DKFZp686G21139; FLJ16313; FLJ22401; FLJ34460; Mindin; spondin 2, extracellular matrix protein; Spondin-2

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Gene Aliases: DIL-1; DIL1; M-SPONDIN; MINDIN; SPON2; UNQ435/PRO866

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UniProt ID: (Human) Q9BUD6

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Entrez Gene ID: (Human) 10417

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lipopolysaccharide binding antigen binding protein binding metal ion binding cell adhesion molecule

Process(es)

mast cell mediated immunity cell adhesion axon guidance opsonization positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production induction of bacterial agglutination innate immune response defense response to fungus defense response to virus positive regulation of macrophage cytokine production cellular response to lipopolysaccharide

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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