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SPON2 Antibody (PA5-59087) in WB
Western blot analysis of SPON2 in control (vector only transfected HEK293T lysate) and SPON2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a SPON2 Polyclonal Antibody (Product # PA5-59087).
Product Details
PA5-59087
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SPON2. Recombinant protein control fragment (Product #RP-96703).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647882
Product Specific Information
Immunogen sequence: HPANSFYYPR LKALPPIARV TLLRLRQSPR AFIPPAPVLP SRDNEIVDSA SVPETPLDCE VSLWSSWGLC GGHCGRLGTK SRTRYVRVQP ANNGS
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.
Target Information
Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Differentially expressed in cancerous and non-cancerous lung cells 1; DIL-1; DKFZp686G21139; FLJ16313; FLJ22401; FLJ34460; Mindin; spondin 2, extracellular matrix protein; Spondin-2
Gene Aliases: DIL-1; DIL1; M-SPONDIN; MINDIN; SPON2; UNQ435/PRO866
UniProt ID: (Human) Q9BUD6
Entrez Gene ID: (Human) 10417
mast cell mediated immunity
cell adhesion
axon guidance
opsonization
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
induction of bacterial agglutination
innate immune response
defense response to fungus
defense response to virus
positive regulation of macrophage cytokine production
cellular response to lipopolysaccharide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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