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Immunogen sequence: MHRDSCPLDC KVYVGNLGNN GNKTELERAF GYYGPLRSVW VARNPPGFAF VEFEDPRDAA DAVRELDGRT LCGCRVRVEL SNGEKRSRNR; Positive Samples: U-87MG, HeLa, K-562, NIH/3T3, PC-12, Mouse brain, Mouse thymus, Rat brain; Cellular Location: Cytoplasm, Nucleus
SR proteins appear to be recruited from nuclear "speckles", in which they are concentrated, to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: pre-mRNA splicing factor SRp20; Pre-mRNA-splicing factor SRP20; Protein X16; Serine/arginine-rich splicing factor 3; Splicing factor, arginine/serine-rich 3; splicing factor, arginine/serine-rich 3 (SRp20); splicing factor, arginine/serine-rich, 20-kD
Gene Aliases: AL024116; SFRS3; SRP20; SRSF3; X16
UniProt ID: (Human) P84103, (Mouse) P84104
Entrez Gene ID: (Human) 6428, (Rat) 361814, (Mouse) 20383
Molecular Function:
RNA splicing factor
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