Product References
Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase.
Stem cells translational medicine
Hekman KE,Koss KM,Ivancic DZ,He C,Wertheim JA
41-4000 was used in Immunocytochemistry to find that autophagy activity was stimulated during differentiation but stagnated in mature iPSC-ECs.
Fri Nov 18 00:00:00 EST 2022
Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase.
Stem cells translational medicine
Hekman KE,Koss KM,Ivancic DZ,He C,Wertheim JA
41-4000 was used in Immunocytochemistry to find that autophagy activity was stimulated during differentiation but stagnated in mature iPSC-ECs.
Fri Nov 18 00:00:00 EST 2022
Generation of three induced pluripotent stem cells lines from patients with esophageal atresia/tracheoesophageal fistula type C.
Stem cell research
Raad S,David A,Chung W,Faure C
41-4000 was used in Immunocytochemistry to generate three iPSC cell lines using peripheral blood mononuclear cells (PBMCs) from EA/TEF type C patients.
Fri Apr 01 00:00:00 EDT 2022
Syndromic RNA polymerase II insufficiency: Generation of a human induced pluripotent stem cell line (UUIGPi002A-5) with a heterozygous disruption of POLR2A.
Stem cell research
Schuster J,de Guidi C,Fatima A,Sobol M,Dahl N
41-4000 was used in Flow cytometry/Cell sorting to generate an iPSC line KICRi002A-5 with a heterozygous truncating POLR2A variant resulting in reduced POLR2A mRNA levels.
Wed Dec 01 00:00:00 EST 2021
Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases.
Communications biology
Ye T,Duan Y,Tsang HWS,Xu H,Chen Y,Cao H,Chen Y,Fu AKY,Ip NY
41-4000 was used in Immunocytochemistry to demonstrate a simple and precise method to simultaneously generate iPSC lines with different gene dosages using paired Cas9 nickases.
Fri Feb 12 00:00:00 EST 2021
Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution.
Cell
Cowan CS,Renner M,De Gennaro M,Gross-Scherf B,Goldblum D,Hou Y,Munz M,Rodrigues TM,Krol J,Szikra T,Cuttat R,Waldt A,Papasaikas P,Diggelmann R,Patino-Alvarez CP,Galliker P,Spirig SE,Pavlinic D,Gerber-Hollbach N,Schuierer S,Srdanovic A,Balogh M,Panero R,Kusnyerik A,Szabo A,Stadler MB,Orgül S,Picelli S,Hasler PW,Hierlemann A,Scholl HPN,Roma G,Nigsch F,Roska B
Published figure using SSEA4 monoclonal antibody (Product # 41-4000) in Immunocytochemistry
Thu Sep 17 00:00:00 EDT 2020
Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease.
Journal of medicinal chemistry
de Matos AM,Blázquez-Sánchez MT,Bento-Oliveira A,de Almeida RFM,Nunes R,Lopes PEM,Machuqueiro M,Cristóvão JS,Gomes CM,Souza CS,El Idrissi IG,Colabufo NA,Diniz A,Marcelo F,Oliveira MC,López Ó,Fernandez-Bolaños JG,Dätwyler P,Ernst B,Ning K,Garwood C,Chen B,Rauter AP
41-4000 was used in Immunocytochemistry to investigate the potential of nature-inspired glucosylpolyphenols against relevant targets, including islet amyloid polypeptide, glucosidases, and cholinesterases.
Thu Oct 22 00:00:00 EDT 2020
Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons.
Neural regeneration research
Chen ST,Lai WJ,Zhang WJ,Chen QP,Zhou LB,So KF,Shi LL
Published figure using SSEA4 monoclonal antibody (Product # 41-4000) in Immunocytochemistry
Tue Dec 01 00:00:00 EST 2020
Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons.
Neural regeneration research
Chen ST,Lai WJ,Zhang WJ,Chen QP,Zhou LB,So KF,Shi LL
Published figure using SSEA4 monoclonal antibody (Product # 41-4000) in Immunocytochemistry
Tue Dec 01 00:00:00 EST 2020
Generation of two iPSC lines (KAUSTi001-A, KAUSTi002-A) from a rare high-grade Klinefelter Syndrome patient (49-XXXXY) carrying a balanced translocation t(4,11) (q35,q23).
Stem cell research
Alowaysi M,Fiacco E,Astro V,Adamo A
41-4000 was used in Immunocytochemistry to generate two iPSC lines 48-XXXY and 49-XXXXY from a non-mosaic 49-XXXXY KS patient carrying a balanced translocation t(4,11) (q35,q23).
Tue Dec 01 00:00:00 EST 2020
Generation of a human Neurochondrin deficient iPSC line KICRi002-A-3 using CRISPR/Cas9.
Stem cell research
Fatima A,Schuster J,Akram T,Sobol M,Hoeber J,Dahl N
41-4000 was used in Flow Cytometry to generate a Neurochondrin deficient human iPSC line KICRi002-A-3 carrying a homozygous 752 bp deletion / 2 bp insertion in the NCDN gene.
Wed Apr 01 00:00:00 EDT 2020
Generation of iPSC lines (KAUSTi011-A, KAUSTi011-B) from a Saudi patient with epileptic encephalopathy carrying homozygous mutation in the GLP1R gene.
Stem cell research
Alowaysi M,Astro V,Fiacco E,Alzahrani F,Alkuraya FS,Adamo A
41-4000 was used in Immunocytochemistry to establish two iPSC lines from a patient harbouring a rare homozygous splice site variant in GLP1R for use as a model to study the molecular pathology of GLP1R dysfunction.
Mon Dec 28 00:00:00 EST 2020
Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B).
Stem cell research
Alowaysi M,Fiacco E,Astro V,Adamo A
41-4000 was used in Flow Cytometry to describe the derivation of multiple 47-XXY iPSC lines from three unrelated KS patients to study the impact of supernumerary X chromosome during early development.
Tue Dec 01 00:00:00 EST 2020
Establishment of an iPSC cohort from three unrelated 47-XXY Klinefelter Syndrome patients (KAUSTi007-A, KAUSTi007-B, KAUSTi009-A, KAUSTi009-B, KAUSTi010-A, KAUSTi010-B).
Stem cell research
Alowaysi M,Fiacco E,Astro V,Adamo A
41-4000 was used in Flow Cytometry to describe the derivation of multiple 47-XXY iPSC lines from three unrelated KS patients to study the impact of supernumerary X chromosome during early development.
Tue Dec 01 00:00:00 EST 2020
Incontinentia pigmenti: Generation of an IKBKG deficient human iPSC line (KICRi002-A-1) on a 46,XY background using CRISPR/Cas9.
Stem cell research
Fatima A,Schuster J,Akram T,González CM,Sobol M,Hoeber J,Dahl N
41-4000 was used in Immunocytochemistry to generate an IKBKG knock-out iPSC line (KICRi002-A-1) on a 46,XY background using CRISPR/Cas9 technology.
Wed Apr 01 00:00:00 EDT 2020
Generation of human induced pluripotent stem cell (iPSC) lines (UUMCBi001-A, UUMCBi002-A) from two healthy donors.
Stem cell research
Vasylovska S,Schuster J,Brboric A,Carlsson PO,Dahl N,Lau J
41-4000 was used in Immunocytochemistry-immunofluorescence to generate two human iPSC lines from dermal fibroblasts of two healthy females using Sendai virus reprogramming.
Wed Dec 09 00:00:00 EST 2020
Mesenchymal Stem Cell Therapy in Submandibular Salivary Gland Allotransplantation: Experimental Study.
Transplantation
Almansoori AA,Khentii N,Kim B,Kim SM,Lee JH
41-4000 was used in Immunocytochemistry to evaluate the effect of allogeneic mesenchymal stem cell (MSC) therapy on the survival of allotransplanted submandibular salivary glands.
Sat Jun 01 00:00:00 EDT 2019
Optimizing methods for human testicular tissue cryopreservation and spermatogonial stem cell isolation.
Journal of cellular biochemistry
Moraveji SF,Esfandiari F,Sharbatoghli M,Taleahmad S,Nikeghbalian S,Shahverdi A,Baharvand H
41-4000 was used in Immunocytochemistry-immunoflourescence to establish optimised protocols for cryopreservation of human testicular tissue and isolation of spermatogonial stem cells from cryopreserved tissue.
Tue Jan 01 00:00:00 EST 2019
Optimizing methods for human testicular tissue cryopreservation and spermatogonial stem cell isolation.
Journal of cellular biochemistry
Moraveji SF,Esfandiari F,Sharbatoghli M,Taleahmad S,Nikeghbalian S,Shahverdi A,Baharvand H
41-4000 was used in Immunocytochemistry-immunoflourescence to establish optimised protocols for cryopreservation of human testicular tissue and isolation of spermatogonial stem cells from cryopreserved tissue.
Tue Jan 01 00:00:00 EST 2019
Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons.
Frontiers in neuroanatomy
Huang G,Chen S,Chen X,Zheng J,Xu Z,Doostparast Torshizi A,Gong S,Chen Q,Ma X,Yu J,Zhou L,Qiu S,Wang K,Shi L
41-4000 was used in Immunocytochemistry-immunoflourescence to study the effects of SHANK3 loss of function mutations on neurodevelopment.
Thu Oct 01 00:00:00 EDT 2020
Generation of human induced pluripotent stem cell (iPSC) lines from three patients with von Hippel-Lindau syndrome carrying distinct VHL gene mutations.
Stem cell research
Schuster J,Fatima A,Schwarz F,Klar J,Laan L,Dahl N
41-4000 was used in Flow Cytometry to offer a useful resource to study disease pathophysiology and for anti-cancer drug development.
Mon Jul 01 00:00:00 EDT 2019
Generation of three human induced pluripotent stem cell (iPSC) lines from three patients with Dravet syndrome carrying distinct SCN1A gene mutations.
Stem cell research
Schuster J,Fatima A,Sobol M,Norradin FH,Laan L,Dahl N
41-4000 was used in Flow Cytometry, Immunocytochemistry to show that these iPSC lines offer a useful resource to investigate the molecular mechanisms underlying Nav1.1 haploinsufficiency and for drug development to improve treatment of DS patients.
Thu Aug 01 00:00:00 EDT 2019
Generation of three human induced pluripotent stem cell (iPSC) lines from three patients with Dravet syndrome carrying distinct SCN1A gene mutations.
Stem cell research
Schuster J,Fatima A,Sobol M,Norradin FH,Laan L,Dahl N
41-4000 was used in Flow Cytometry, Immunocytochemistry to show that these iPSC lines offer a useful resource to investigate the molecular mechanisms underlying Nav1.1 haploinsufficiency and for drug development to improve treatment of DS patients.
Thu Aug 01 00:00:00 EDT 2019
Retrograde monosynaptic tracing through an engineered human embryonic stem cell line reveals synaptic inputs from host neurons to grafted cells.
Cell regeneration (London, England)
Xing Q,Lin A,Su Z,Liu C,Huang W,Guo W,Pan G,Guo Y,Zhong X
41-4000 was used in Flow cytometry/Cell sorting to provide an efficient approach to analyze transplant connectivity for the comprehensive assessment of host-donor cell innervation.
Sat Jun 01 00:00:00 EDT 2019
Characterization of the structure, cells, and cellular mechanobiological response of human plantar fascia.
Journal of tissue engineering
Zhang J,Nie D,Rocha JL,Hogan MV,Wang JH
41-4000 was used in Immunocytochemistry-immunoflourescence to characterise the structure, cells, and cellular mechanobiological response of human plantar fascia.
Mon Sep 28 00:00:00 EDT 2020
Identification and Characterizations of Annulus Fibrosus-Derived Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Guo Q,Zhou P,Li B
41-4000 was used in Immunocytochemistry to find that there exists a subpopulation of cells, which form colonies in vitro and could self-renew, in AF tissue.
Tue Apr 23 00:00:00 EDT 2019
Maintenance of Tendon Stem/Progenitor Cells in Culture.
Methods in molecular biology (Clifton, N.J.)
Zhang J,Wang JH
41-4000 was used in Immunocytochemistry-immunofluorescence to developed two effective methods, namely culturing TSCs in hypoxic condition, or in growth media supplemented with low levels of PGE2, to maintain and prolong the stemness of TSCs in culture.
Tue Apr 23 00:00:00 EDT 2019
Generation of trophoblast-like cells from the amnion in vitro: A novel cellular model for trophoblast development.
Placenta
Wei Y,Zhou X,Huang W,Long P,Xiao L,Zhang T,Zhong M,Pan G,Ma Y,Yu Y
41-4000 was used in Flow cytometry/Cell sorting to provide an in vitro cellular model to study early trophoblast development for specific individuals, by using the feasible amnion.
Wed Mar 01 00:00:00 EST 2017
A novel bioactive osteogenesis scaffold delivers ascorbic acid, β-glycerophosphate, and dexamethasone in vivo to promote bone regeneration.
Oncotarget
Wang C,Cao X,Zhang Y
Published figure using SSEA4 monoclonal antibody (Product # 41-4000) in Immunofluorescence
Tue May 09 00:00:00 EDT 2017
Mouse iPSC generated with porcine reprogramming factors as a model for studying the effects of non-silenced heterologous transgenes on pluripotency.
Journal of stem cells & regenerative medicine
Petkov SG,Glage S,Niemann H
41-4000 was used in Immunocytochemistry to evaluate the ability of transposon-based vectors with porcine pluripotency factors to reprogram mouse foetal fibroblasts to pluripotency.
Wed Sep 30 00:00:00 EDT 2020
Harmful Effects of Leukocyte-Rich Platelet-Rich Plasma on Rabbit Tendon Stem Cells In Vitro.
The American journal of sports medicine
Zhang L,Chen S,Chang P,Bao N,Yang C,Ti Y,Zhou L,Zhao J
41-4000 was used in immunocytochemistry to study rabbit tendon stem cells in vitro by harmful effects of leukocyte-rich platelet-rich plasma
Mon Aug 01 00:00:00 EDT 2016
Differential Characterization of Two Kinds of Stem Cells Isolated from Rabbit Nucleus Pulposus and Annulus Fibrosus.
Stem cells international
Sang C,Cao X,Chen F,Yang X,Zhang Y
41-4000 was used in immunocytochemistry identify and characterize stem cells in the nucleus pulposus and annulus fibrosus
Sun Apr 10 00:00:00 EDT 2022
Comparative epigenetic evaluation of human embryonic stem and induced pluripotent cells.
The International journal of developmental biology
Favaedi R,Shahhoseini M,Pakzad M,Mollamohammadi S,Baharvand H
41-4000 was used in Immunocytochemistry to evaluate the epigenetic profiles of human embryonic stem and induced pluripotent cells.
Wed Jan 31 00:00:00 EST 2018
A study to identify and characterize the stem/progenitor cell in rabbit meniscus.
Cytotechnology
Huang H,Wang S,Gui J,Shen H
41-4000 was used in immunocytochemistry to examine the role of meniscus-derived stromal cells in healing
Sat Oct 01 00:00:00 EDT 2016
X-Chromosome Inactivation Analysis in Different Cell Types and Induced Pluripotent Stem Cells Elucidates the Disease Mechanism in a Rare Case of Mucopolysaccharidosis Type II in a Female.
Folia biologica
Řeboun M,Rybová J,Dobrovolný R,Včelák J,Veselková T,Štorkánová G,Mušálková D,Hřebíček M,Ledvinová J,Magner M,Zeman J,Pešková K,Dvořáková L
41-4000 was used in immunocytochemistry to elucidate the mechanism responsible for a rare case of a female with mucopolysaccharidosis type II via X-chromosome inactivation analysis in different cell types and induced pluripotent stem cells
Wed Mar 08 00:00:00 EST 2017
High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.
Molecular & cellular proteomics : MCP
Kanderova V,Kuzilkova D,Stuchly J,Vaskova M,Brdicka T,Fiser K,Hrusak O,Lund-Johansen F,Kalina T
414000 was used to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients
Fri Apr 01 00:00:00 EDT 2016
Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.
Frontiers in cellular neuroscience
Alves CJ,Dariolli R,Jorge FM,Monteiro MR,Maximino JR,Martins RS,Strauss BE,Krieger JE,Callegaro D,Chadi G
41-4000 was used in immunocytochemistry to research human iPS-derived motor neurons from sporadic ALS patients for gene expression and a strong association between neurodegeneration and mitochondrial functions
Mon Aug 24 00:00:00 EDT 2015
GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment.
Cell regeneration (London, England)
Huang K,Du J,Ma N,Liu J,Wu P,Dong X,Meng M,Wang W,Chen X,Shi X,Chen Q,Yang Z,Chen S,Zhang J,Li Y,Li W,Zheng Y,Cai J,Li P,Sun X,Wang J,Pei D,Pan G
Published figure using SSEA4 monoclonal antibody (Product # 41-4000) in Flow Cytometry
Thu Aug 06 00:00:00 EDT 2015
Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair.
BMC musculoskeletal disorders
Ding Z,Huang H
41-4000 was used in immunocytochemistry to test if mesenchymal stem cells that reside in meniscus maintain specific traits are better for meniscus regeneration
Sat Mar 21 00:00:00 EDT 2015
Affinity of monoclonal antibodies for Globo-series glycans.
Carbohydrate research
Eller CH,Yang G,Ouerfelli O,Raines RT
41-4000 was used to assess the affinity of monoclonal antibodies to the glycans present in SSEA-4 and Globo H
Thu Oct 09 00:00:00 EDT 2014
Prostaglandin E2 (PGE2) exerts biphasic effects on human tendon stem cells.
PloS one
Zhang J,Wang JH
41-4000 was used in immunocytochemistry to determine the biphasic effects of PGE2 on human tendon stem/progenitor cells.
Sun Dec 28 00:00:00 EST 2014
Identification of rabbit annulus fibrosus-derived stem cells.
PloS one
Liu C,Guo Q,Li J,Wang S,Wang Y,Li B,Yang H
41-4000 was used in immunocytochemistry to isolate and characterize mesenchymal stem cells from rabbit annulus fibrosus tissue
Wed Jun 10 00:00:00 EDT 2015
Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity.
PloS one
Alvarez-Gonzalez C,Duggleby R,Vagaska B,Querol S,Gomez SG,Ferretti P,Madrigal A
41-4000 was used in immunocytochemistry to isolate, characterize, and expand embryonic-like stem cells from human umbilical cord blood.
Thu Apr 24 00:00:00 EDT 2014
Cellular characterization of human pluripotent stem cells.
Methods in molecular biology (Clifton, N.J.)
Quintanilla RH
Thu Sep 19 00:00:00 EDT 2013
Applications of quantitative polymerase chain reaction protein assays during reprogramming.
Stem cells and development
Ruff D,MacArthur C,Tran H,Bergseid J,Tian J,Shannon M,Chen SM,Fontes A,Laurent L,Swartzman E,Taliana A,Rao M,Lieu PT
Thu Mar 01 00:00:00 EST 2012
BMP-2 mediates PGE(2) -induced reduction of proliferation and osteogenic differentiation of human tendon stem cells.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Zhang J,Wang JH
41-4000 was used in Immunocytochemistry to investigate the effects of PGE2 on human tendon stem cell proliferation and differentiation, and the molecular mediator of these effects.
Sun Jan 01 00:00:00 EST 2012
Differential properties of human ACL and MCL stem cells may be responsible for their differential healing capacity.
BMC medicine
Zhang J,Pan T,Im HJ,Fu FH,Wang JH
41-4000 was used in immunocytochemistry to characterize stem cells in human anterior cruciate and medial collateral ligaments.
Thu Jun 02 00:00:00 EDT 2011
Clathrin assembly proteins AP180 and CALM in the embryonic rat brain.
The Journal of comparative neurology
Schwartz CM,Cheng A,Mughal MR,Mattson MP,Yao PJ
41-4000 was used in immunocytochemistry to investigate the changes of clathrin assembly proteins AP180 and CALM during neuronal development
Wed Sep 15 00:00:00 EDT 2010
Characterization of differential properties of rabbit tendon stem cells and tenocytes.
BMC musculoskeletal disorders
Zhang J,Wang JH
41-4000 was used in immunocytochemistry to characterize rabbit tendon stem/progenitor cells
Mon Jan 18 00:00:00 EST 2010
Characterization of differential properties of rabbit tendon stem cells and tenocytes.
BMC musculoskeletal disorders
Zhang J,Wang JH
41-4000 was used in immunocytochemistry to characterize rabbit tendon stem/progenitor cells
Mon Jan 18 00:00:00 EST 2010
Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells.
The EMBO journal
Kannagi R,Cochran NA,Ishigami F,Hakomori S,Andrews PW,Knowles BB,Solter D
41-4000 was used in immunocytochemistry to use MC631 and MC813-70 to study glycolipids in human teratocarcinoma
Thu Mar 29 00:00:00 EST 1984