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Immunogen sequence: REDSFYFPIP EKKEPCLQGE AESKASKLFG NYSRDQPIFL RLEDYFWVKT PSAYELPYGT KGSEDLLLRV LAITSSSIPK NIQSLRCRRC VVVGNGHRLR NSSLGDAINK YDVVIRLNNA PVAGYEGDVG SKTTMRLFYP ESAHFDPKVE NNPDTLLVLV AFKAMDFHWI ETILSDKKRV RKGFWKQPPL IWDVNPKQIR ILNPFFMEIA ADKLLSLPMQ QPRKIKQKPT TGLLAITLAL H; Positive Samples: Mouse ovary, Rat liver; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein
Synthesis of alpha-2, 3-linked sialic acid to Gal(beta-1, 3)GalNAc is mediated by at least 3 distinct beta-galactoside alpha-2, 3-sialyltransferases (EC 2.4.99.4), including ST3GAL4. In contrast, only a single gene encodes the beta-galactoside alpha-2, 6-sialyltransferase, ST6GAL1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha 2,3-sialyltransferase IV; Alpha 2,3-ST 4; alpha-2,3-sialyltransferase ST3Gal IV; beta-galactoside alpha-2,3-sialyltransferase 4; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; FLJ11867; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; Gal-beta-1,4-GlcNAc-alpha-2,3-sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; Sialyltransferase 4C; sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase); sialyltransferase 4C (beta-galactoside alpha-2,3-sialytransferase); SIAT4-C; ST3Gal IV; ST3GalIV
Gene Aliases: Siat4c; St3gal4
UniProt ID: (Mouse) Q91Y74, (Rat) P61131
Entrez Gene ID: (Mouse) 20443, (Rat) 363040
Molecular Function:
transferase
metabolite interconversion enzyme
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