Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: VLCWLYIFP VYRLPNEKEI VQGVLQQGTA WRRNQTAARA FRKQMEDCCD PAHLFAMTKM NSPMGKSMWY DGEFLYSFTI DNSTYSLFPQ ATPFQLPLK (39-136 aa encoded by BC126162)
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: alpha-2, 8-sialyltransferase; Alpha-2,8-sialyltransferase 8A; Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; disialoganglioside (GD3) synthase; Ganglioside GD3 synthase; Ganglioside GT3 synthase; ganglioside-specific alpha-2,8-polysialyltransferase; GD3 synthase; sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A; sialyltransferase 8 A; Sialyltransferase 8A; sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase); Sialyltransferase St8Sia I; sialytransferase St8Sia I; SIAT8-A; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1; ST8Sia I; ST8SiaI
Gene Aliases: 9330109E03Rik; GD3S; Sia-T; SIAT8; SIAT8-A; SIAT8A; ST8SIA1; ST8SiaI
UniProt ID: (Human) Q92185, (Mouse) Q64687
Entrez Gene ID: (Human) 6489, (Mouse) 20449
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