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Product Details
22673-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STARS/ABRA Fusion Protein Ag18456 (1-381 aa encoded by BC105103)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAPGEKESG EGPAKSALRK IRTATLVISL ARGWQQWANE NSIRQAQEPT GWLPGGTQDS PQAPKPITPP TSHQKAQSAP KSPPRLPEGH GDGQSSEKAP EVSHIKKKEV SKTVVSKTYE RGGDVSHLSH RYERDAGVLE PGQPENDIDR ILHSHGSPTR RRKCANLVSE LTKGWRVMEQ EEPTWRSDSV DTEDSGYGGE AEERPEQDGV QVAVVRIKRP LPSQVNRFTE KLNCKAQQKY SPVGNLKGRW QQWADEHIQS QKLNPFSEEF DYELAMSTRL HKGDEGYGRP KEGTKTAERA KRAEEHIYRE MMDMCFIICT MARHRRDGKI QVTFGDLFDR YVRISDKVVG ILMRARKHGL VDFEGEMLWQ GRDDHVVITL LK (1-381 aa encoded by BC105103)
Target Information
Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ABRA; actin-binding Rho activating protein; Actin-binding Rho-activating protein; STARS; Striated muscle activator of Rho-dependent signaling
Gene Aliases: ABRA; C130068O12Rik; STARS
UniProt ID: (Human) Q8N0Z2, (Mouse) Q8BUZ1
Entrez Gene ID: (Human) 137735, (Mouse) 223513
protein import into nucleus, translocation
transcription, DNA-templated
regulation of transcription, DNA-templated
transport
protein transport
positive regulation of Rho protein signal transduction
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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