Product References
Type I and III interferons shape the retinal cytokine network and barrier function in an in vitro model of ocular toxoplasmosis.
Frontiers in immunology
Geiller B,Greigert V,Hillenbrand CA,Gommenginger C,Beal L,Brunet J,Filisetti D,Villard O,Denis J,Pfaff AW
AHO0832 was used in Western Blotting to show that stimulation with type I and III interferons did not limit parasite proliferation in retinal cells we tested.
Mon May 22 00:00:00 EDT 2023
Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells.
Viruses
Zhang Y,Gargan S,Roche FM,Frieman M,Stevenson NJ
AHO0832 was used in Immunocytochemistry-immunofluorescence to show that in lung alveolar A549 epithelial cells expression of MERS-CoV-nsp2 and SARS-CoV-1-nsp14, but not MERS-CoV-nsp5, increased basal levels of total and phosphorylated STAT1 STAT2 protein, but reduced IFN-α-mediated phosphorylation of STAT1-3 and induction of MxA.
Wed Mar 23 00:00:00 EDT 2022
Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells.
Viruses
Zhang Y,Gargan S,Roche FM,Frieman M,Stevenson NJ
AHO0832 was used in Immunocytochemistry-immunofluorescence to show that in lung alveolar A549 epithelial cells expression of MERS-CoV-nsp2 and SARS-CoV-1-nsp14, but not MERS-CoV-nsp5, increased basal levels of total and phosphorylated STAT1 STAT2 protein, but reduced IFN-α-mediated phosphorylation of STAT1-3 and induction of MxA.
Wed Mar 23 00:00:00 EDT 2022
Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes.
Molecular neurodegeneration
Kim DW,Tu KJ,Wei A,Lau AJ,Gonzalez-Gil A,Cao T,Braunstein K,Ling JP,Troncoso JC,Wong PC,Blackshaw S,Schnaar RL,Li T
AHO0832 was used in ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to suggest that both Aβ and tau pathologies are required for the disease stage-specific induction of early-stage AD-Associated Microglia (EADAM) and late-stage AD-Associated Microglia (LADAM), and reveal Siglecs as biomarkers of Alzheimer's disease progression.
Sat Dec 17 00:00:00 EST 2022
MiR-342 controls Mycobacterium tuberculosis susceptibility by modulating inflammation and cell death.
EMBO reports
Fu B,Lin X,Tan S,Zhang R,Xue W,Zhang H,Zhang S,Zhao Q,Wang Y,Feldman K,Shi L,Zhang S,Nian W,Chaitanya Pavani K,Li Z,Wang X,Wu H
Published figure using STAT1 monoclonal antibody (Product # AHO0832) in Western Blot
Mon Sep 06 00:00:00 EDT 2021
SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon.
PLoS pathogens
Shemesh M,Aktepe TE,Deerain JM,McAuley JL,Audsley MD,David CT,Purcell DFJ,Urin V,Hartmann R,Moseley GW,Mackenzie JM,Schreiber G,Harari D
Published figure using STAT1 monoclonal antibody (Product # AHO0832) in Western Blot
Sun Aug 01 00:00:00 EDT 2021
Metabolites Profiling of Melanoma Interstitial Fluids Reveals Uridine Diphosphate as Potent Immune Modulator Capable of Limiting Tumor Growth.
Frontiers in cell and developmental biology
Vecchio E,Caiazza C,Mimmi S,Avagliano A,Iaccino E,Brusco T,Nisticò N,Maisano D,Aloisio A,Quinto I,Renna M,Divisato G,Romano S,Tufano M,D'Agostino M,Vigliar E,Iaccarino A,Mignogna C,Andreozzi F,Mannino GC,Spiga R,Stornaiuolo M,Arcucci A,Mallardo M,Fiume G
AHO0832 was used in Western Blot to deploy a metabolomic approach to analyze the composition of melanoma tumor interstitial fluid and compared it to the plasma of C57BL6 mice, engrafted or not with B16-melanoma cells.
Tue Oct 05 00:00:00 EDT 2021
Metabolites Profiling of Melanoma Interstitial Fluids Reveals Uridine Diphosphate as Potent Immune Modulator Capable of Limiting Tumor Growth.
Frontiers in cell and developmental biology
Vecchio E,Caiazza C,Mimmi S,Avagliano A,Iaccino E,Brusco T,Nisticò N,Maisano D,Aloisio A,Quinto I,Renna M,Divisato G,Romano S,Tufano M,D'Agostino M,Vigliar E,Iaccarino A,Mignogna C,Andreozzi F,Mannino GC,Spiga R,Stornaiuolo M,Arcucci A,Mallardo M,Fiume G
AHO0832 was used in Western Blot to deploy a metabolomic approach to analyze the composition of melanoma tumor interstitial fluid and compared it to the plasma of C57BL6 mice, engrafted or not with B16-melanoma cells.
Tue Oct 05 00:00:00 EDT 2021
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
Cancer discovery
Clarke M,Mackay A,Ismer B,Pickles JC,Tatevossian RG,Newman S,Bale TA,Stoler I,Izquierdo E,Temelso S,Carvalho DM,Molinari V,Burford A,Howell L,Virasami A,Fairchild AR,Avery A,Chalker J,Kristiansen M,Haupfear K,Dalton JD,Orisme W,Wen J,Hubank M,Kurian KM,Rowe C,Maybury M,Crosier S,Knipstein J,Schüller U,Kordes U,Kram DE,Snuderl M,Bridges L,Martin AJ,Doey LJ,Al-Sarraj S,Chandler C,Zebian B,Cairns C,Natrajan R,Boult JKR,Robinson SP,Sill M,Dunkel IJ,Gilheeney SW,Rosenblum MK,Hughes D,Proszek PZ,Macdonald TJ,Preusser M,Haberler C,Slavc I,Packer R,Ng HK,Caspi S,Popović M,Faganel Kotnik B,Wood MD,Baird L,Davare MA,Solomon DA,Olsen TK,Brandal P,Farrell M,Cryan JB,Capra M,Karremann M,Schittenhelm J,Schuhmann MU,Ebinger M,Dinjens WNM,Kerl K,Hettmer S,Pietsch T,Andreiuolo F,Driever PH,Korshunov A,Hiddingh L,Worst BC,Sturm D,Zuckermann M,Witt O,Bloom T,Mitchell C,Miele E,Colafati GS,Diomedi-Camassei F,Bailey S,Moore AS,Hassall TEG,Lowis SP,Tsoli M,Cowley MJ,Ziegler DS,Karajannis MA,Aquilina K,Hargrave DR,Carceller F,Marshall LV,von Deimling A,Kramm CM,Pfister SM,Sahm F,Baker SJ,Mastronuzzi A,Carai A,Vinci M,Capper D,Popov S,Ellison DW,Jacques TS,Jones DTW,Jones C
AHO0832 was used in Immunocytochemistry to collect the largest series of infant gliomas (exclusive of pilocytic astrocytomas) assembled to date and present a classification system based on integrated methylation profiling, fusion gene analysis, mutation detection, and histologic review, with preclinical and clinical evidence of effective targeting of the driving alterations in these unique entities.
Wed Jul 01 00:00:00 EDT 2020
STAT1 expression and HPV16 viral load predict cervical lesion progression.
Oncology letters
Wu S,Wu Y,Lu Y,Yue Y,Cui C,Yu M,Wang S,Liu M,Zhao Y,Sun Z
AHO0832 was used in Immunohistochemistry to determine the association between STAT1 and human papillomavirus (HPV)16 in cervical lesions.
Thu Oct 01 00:00:00 EDT 2020
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling.
mBio
Fu B,Xue W,Zhang H,Zhang R,Feldman K,Zhao Q,Zhang S,Shi L,Pavani KC,Nian W,Lin X,Wu H
AHO0832 was used in Western Blotting to contribution to the understanding of the immune escape of M. tuberculosis, and they provide a theoretical basis for the development of therapeutic approaches for drug-resistant TB.
Tue Jun 02 00:00:00 EDT 2020
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling.
mBio
Fu B,Xue W,Zhang H,Zhang R,Feldman K,Zhao Q,Zhang S,Shi L,Pavani KC,Nian W,Lin X,Wu H
AHO0832 was used in Western Blotting to contribution to the understanding of the immune escape of M. tuberculosis, and they provide a theoretical basis for the development of therapeutic approaches for drug-resistant TB.
Tue Jun 02 00:00:00 EDT 2020
PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure.
Cell death & disease
Fu B,Yin S,Lin X,Shi L,Wang Y,Zhang S,Zhao Q,Li Z,Yang Y,Wu H
Published figure using STAT1 monoclonal antibody (Product # AHO0832) in Western Blot
Fri Sep 25 00:00:00 EDT 2020
LncRNA PLAC2 down-regulates RPL36 expression and blocks cell cycle progression in glioma through a mechanism involving STAT1.
Journal of cellular and molecular medicine
Hu YW,Kang CM,Zhao JJ,Nie Y,Zheng L,Li HX,Li X,Wang Q,Qiu YR
Published figure using STAT1 monoclonal antibody (Product # AHO0832) in Immunoprecipitation
Mon Jan 01 00:00:00 EST 2018
LncRNA PLAC2 down-regulates RPL36 expression and blocks cell cycle progression in glioma through a mechanism involving STAT1.
Journal of cellular and molecular medicine
Hu YW,Kang CM,Zhao JJ,Nie Y,Zheng L,Li HX,Li X,Wang Q,Qiu YR
Published figure using STAT1 monoclonal antibody (Product # AHO0832) in Immunoprecipitation
Mon Jan 01 00:00:00 EST 2018
Endothelial IL-33 Expression Is Augmented by Adenoviral Activation of the DNA Damage Machinery.
Journal of immunology (Baltimore, Md. : 1950)
Stav-Noraas TE,Edelmann RJ,Poulsen LC,Sundnes O,Phung D,Küchler AM,Müller F,Kamen AA,Haraldsen G,Kaarbø M,Hol J
AHO0832 was used in western blot to identify factors that contribute to adenoviral transduction stimulation of IL-33 in endothelial cells
Sat Apr 15 00:00:00 EDT 2017
PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.
PloS one
Yu J,Li X,Wang Y,Li B,Li H,Li Y,Zhou W,Zhang C,Wang Y,Rao Z,Bartlam M,Cao Y
Mon Nov 28 00:00:00 EST 2011
PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.
PloS one
Yu J,Li X,Wang Y,Li B,Li H,Li Y,Zhou W,Zhang C,Wang Y,Rao Z,Bartlam M,Cao Y
Mon Nov 28 00:00:00 EST 2011