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Product Details
H00011075-M03A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgM, kappa
Class
Monoclonal
Type
Antibody
Clone
2B2
Immunogen
STMN2 (NP_008960, 1 a.a. approximately 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MAKTAMAYKE KMKELSMLSL ICSCFYPEPR NINIYTYDDM EVKQINKRAS GQAFELILKP PSPISEAPRT LASPKKKDLS LEEIQKKLEA
Target Information
STMN2, also known as SCG-10, is a neuronal growth-associated protein that shares significant amino acid sequence similarity with the phosphoprotein stathmin. STMN2 may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neuron-specific growth-associated protein; neuronal growth-associated protein (silencer element); Protein SCG10; SGC10; Stathmin-2; stathmin-like 2; superior cervical ganglia, neural specific 10; Superior cervical ganglion-10 protein
Gene Aliases: SCG10; SCGN10; STMN2
UniProt ID: (Human) Q93045
Entrez Gene ID: (Human) 11075
negative regulation of microtubule depolymerization
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of microtubule polymerization
positive regulation of microtubule depolymerization
cellular response to nerve growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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