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Product Details
H00064220-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STRA6 (AAH25256.1, 1 a.a. approximately 667 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSSQPAGNQT SPGATEDYSY GSWYIDEPQG GEELQPEGEV PSCHTSIPPG LYHACLASLS ILVLLLLAML VRRRQLWPDC VRGRPGLPSP VDFLAGDRPR AVPAAVFMVL LSSLCLLLPD EDALPFLTLA SAPSQDGKTE APRGAWKILG LFYYAALYYP LAACATAGHT AAHLLGSTLS WAHLGVQVWQ RAECPQVPKI YKYYSLLASL PLLLGLGFLS LWYPVQLVRS FSRRTGAGSK GLQSSYSEEY LRNLLCRKKL GSSYHTSKHG FLSWARVCLR HCIYTPQPGF HLPLKLVLSA TLTGTAIYQV ALLLLVGVVP TIQKVRAGVT TDVSYLLASF GIVLSEDKQE VVELVKHHLW ALEVCYISAL VLSCLLTFLV LMRSLVTHRT NLRALHRGAA LDLSPLHRSP HPSRQAIFCW MSFSAYQTAF ICLGLLVQQI IFFLGTTALA FLVLMPVLHG RNLLLFRSLE SSWPFWLTLA LAVILQNMAA HWVFLETHDG HPQLTNRRVL YAATFLLFPL NVLVGAMVAT WRVLLSALYN AIHLGQMDLS LLPPRAATLD PGYYTYRNFL KIEVSQSHPA MTAFCSLLLQ AQSLLPRTMA APQDSLRPGE EDEGMQLLQT KDSMAKGARP GASRGRARWG LAYTLLHNPT LQVFRKTALL GANGAQP
Target Information
STRA6 is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ12541; Receptor for retinol uptake STRA6; Retinoic acid-responsive protein; retinol binding protein 4 receptor; Retinol-binding protein receptor STRA6; stimulated by retinoic acid 6 homolog; stimulated by retinoic acid gene 6 homolog; Stimulated by retinoic acid gene 6 protein; Stimulated by retinoic acid gene 6 protein homolog
Gene Aliases: AI891933; MCOPCB8; MCOPS9; PP14296; STRA6; UNQ3126/PRO10282/PRO19578
UniProt ID: (Human) Q9BX79, (Mouse) O70491
Entrez Gene ID: (Human) 64220, (Mouse) 20897
retinoid metabolic process
blood vessel development
kidney development
pulmonary valve morphogenesis
ventricular septum development
heart development
learning
feeding behavior
lung development
adrenal gland development
female genitalia development
vocal learning
ear development
nose morphogenesis
lung alveolus development
positive regulation of behavior
digestive tract morphogenesis
embryonic digestive tract development
developmental growth
smooth muscle tissue development
artery morphogenesis
cognition
neuromuscular process
vitamin transport
head development
head morphogenesis
face morphogenesis
lung vasculature development
diaphragm development
embryonic camera-type eye formation
eyelid development in camera-type eye
uterus morphogenesis
alveolar primary septum development
pulmonary artery morphogenesis
paramesonephric duct development
ductus arteriosus closure
transport
retinol transport
positive regulation of JAK-STAT cascade
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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