Proteintech

STT3A Polyclonal Antibody

STT3A Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

STT3A Antibody (12034-1-AP) in ICC/IF

Immunofluorescent analysis of HEK-293 cells using 12034-1-AP (STT3A antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

STT3A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

12034-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 13 publications 13 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

STT3A Fusion Protein Ag2698 (475-705 aa encoded by BC020965)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: STWVTSEAY SSPSIVLSAR GGDGSRIIFD DFREAYYWLR HNTPEDAKVM SWWDYGYQIT AMANRTILVD NNTWNNTHIS RVGQAMASTE EKAYEIMREL DVSYVLVIFG GLTGYSSDDI NKFLWMVRIG GSTDTGKHIK ENDYYTPTGE FRVDREGSPV LLNCLMYKMC YYRFGQVYTE AKRPPGFDRV RNAEIGNKDF ELDVLEEAYT TEHWLVRIYK VKDLDNRGLS RT (475-705 aa encoded by BC020965)

Target Information

This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation.

Science advances

Phoomak C,Rinis N,Baro M,Shrimal S,Bennett D,Shaffer SA,Lehrman M,Gilmore R,Contessa JN

Fri Mar 17 00:00:00 EDT 2023

Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis.

American journal of cancer research

Wang SH,Chou WC,Huang HC,Lee TA,Hsiao TC,Wang LH,Huang KB,Kuo CT,Chao CH,Chang SJ,Hsu JM,Weng J,Ren N,Li FA,Lai YJ,Zhou C,Hung MC,Li CW

Thu Nov 17 00:00:00 EST 2022

TGF-β1-Mediated PD-L1 Glycosylation Contributes to Immune Escape via c-Jun/STT3A Pathway in Nasopharyngeal Carcinoma.

Frontiers in oncology

Ma XM,Luo YF,Zeng FF,Su C,Liu X,Li XP,Lu J

Tue Mar 22 00:00:00 EDT 2022

Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.

EBioMedicine

Huang HC,Lai YJ,Liao CC,Yang WF,Huang KB,Lee IJ,Chou WC,Wang SH,Wang LH,Hsu JM,Sun CP,Kuo CT,Wang J,Hsiao TC,Yang PJ,Lee TA,Huang W,Li FA,Shen CY,Lin YL,Tao MH,Li CW

Wed Dec 01 00:00:00 EST 2021

Mettl14-Mediated m⁶A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis.

Cellular and molecular gastroenterology and hepatology

Cao X,Shu Y,Chen Y,Xu Q,Guo G,Wu Z,Shao M,Zhou Y,Chen M,Gong Y,Li C,Shi Y,Bu H

Thu Jan 27 00:00:00 EST 2022

Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis.

Molecular & cellular proteomics : MCP

Wright MT,Kouba L,Plate L

Mon Mar 14 00:00:00 EDT 2022

Intramembrane protease RHBDL4 cleaves oligosaccharyltransferase subunits to target them for ER-associated degradation.

Journal of cell science

Knopf JD,Landscheidt N,Pegg CL,Schulz BL,Kühnle N,Chao CW,Huck S,Lemberg MK

Thu Mar 26 00:00:00 EDT 2020

Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.

Cancer discovery

Song X,Zhou Z,Li H,Xue Y,Lu X,Bahar I,Kepp O,Hung MC,Kroemer G,Wan Y

Tue Dec 01 00:00:00 EST 2020

Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.

Cancer discovery

Song X,Zhou Z,Li H,Xue Y,Lu X,Bahar I,Kepp O,Hung MC,Kroemer G,Wan Y

Tue Dec 01 00:00:00 EST 2020

Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.

Cancer discovery

Song X,Zhou Z,Li H,Xue Y,Lu X,Bahar I,Kepp O,Hung MC,Kroemer G,Wan Y

Tue Dec 01 00:00:00 EST 2020

The AT1 receptor autoantibody causes hypoglycemia in fetal rats via promoting the STT3A-GLUT1-glucose uptake axis in liver.

Molecular and cellular endocrinology

Wang P,He C,Yue M,Wang T,Bai L,Wu Y,Liu D,Wang M,Sun Y,Li Y,Zhang S,Liu H

Tue Dec 01 00:00:00 EST 2020

The AT1 receptor autoantibody causes hypoglycemia in fetal rats via promoting the STT3A-GLUT1-glucose uptake axis in liver.

Molecular and cellular endocrinology

Wang P,He C,Yue M,Wang T,Bai L,Wu Y,Liu D,Wang M,Sun Y,Li Y,Zhang S,Liu H

Tue Dec 01 00:00:00 EST 2020

The AT1 receptor autoantibody causes hypoglycemia in fetal rats via promoting the STT3A-GLUT1-glucose uptake axis in liver.

Molecular and cellular endocrinology

Wang P,He C,Yue M,Wang T,Bai L,Wu Y,Liu D,Wang M,Sun Y,Li Y,Zhang S,Liu H

Tue Dec 01 00:00:00 EST 2020

The AT1 receptor autoantibody causes hypoglycemia in fetal rats via promoting the STT3A-GLUT1-glucose uptake axis in liver.

Molecular and cellular endocrinology

Wang P,He C,Yue M,Wang T,Bai L,Wu Y,Liu D,Wang M,Sun Y,Li Y,Zhang S,Liu H

Tue Dec 01 00:00:00 EST 2020

A Trace Amount of Galactose, a Major Component of Milk Sugar, Allows Maturation of Glycoproteins during Sugar Starvation.

iScience

Sasaoka N,Imamura H,Kakizuka A

Fri Dec 21 00:00:00 EST 2018

Construction of green fluorescence protein mutant to monitor STT3B-dependent N-glycosylation.

The FEBS journal

Kitajima T,Xue W,Liu YS,Wang CD,Liu SS,Fujita M,Gao XD

Thu Mar 01 00:00:00 EST 2018

Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex.

mBio

Lin DL,Cherepanova NA,Bozzacco L,MacDonald MR,Gilmore R,Tai AW

Tue Jul 18 00:00:00 EDT 2017

Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex.

mBio

Lin DL,Cherepanova NA,Bozzacco L,MacDonald MR,Gilmore R,Tai AW

Tue Jul 18 00:00:00 EDT 2017

Changes in cellular glycosylation of leukemia cells upon treatment with acridone derivatives yield insight into drug action.

Proteomics

Wang Y,Park D,Galermo AG,Gao D,Liu H,Lebrilla CB

Thu Dec 01 00:00:00 EST 2016

Changes in cellular glycosylation of leukemia cells upon treatment with acridone derivatives yield insight into drug action.

Proteomics

Wang Y,Park D,Galermo AG,Gao D,Liu H,Lebrilla CB

Thu Dec 01 00:00:00 EST 2016

Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.

Nature chemical biology

Lopez-Sambrooks C,Shrimal S,Khodier C,Flaherty DP,Rinis N,Charest JC,Gao N,Zhao P,Wells L,Lewis TA,Lehrman MA,Gilmore R,Golden JE,Contessa JN

Thu Dec 01 00:00:00 EST 2016

Bioinformatics

Protein Aliases: B5; dolichyl-diphosphooligosaccharide protein glycotransferase; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; Integral membrane protein 1; integral transmembrane protein 1; MGC9042; Oligosaccharyl transferase subunit STT3A; STT3, subunit of the oligosaccharyltransferase complex, homolog A; STT3A, cataylic subunit of the oligosaccharyltransferase complex; STT3A, subunit of the oligosaccharyltransferase complex (catalytic); transmembrane conserved; Transmembrane protein TMC

View more View less

Gene Aliases: ITM1; STT3-A; STT3A; TMC

View more View less

UniProt ID: (Human) P46977

View more View less

Entrez Gene ID: (Human) 3703

View more View less

Function(s)

dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding glycosyltransferase

Process(es)

protein N-linked glycosylation via asparagine co-translational protein modification post-translational protein modification

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

STT3A Polyclonal Antibody

STT3A Antibody (12034-1-AP) in ICC/IF

Product Details

12034-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!