Proteintech

SUOX Polyclonal Antibody

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Antibody Testing Data (8)

SUOX Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

SUOX Antibody (15075-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using SUOX antibody 15075-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

SUOX Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SUOX Antibody in Immunoprecipitation (IP)

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Product Details

15075-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SUOX Fusion Protein Ag7146 (182-545 aa encoded by BC065193)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.75 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RHPALKVNS QRPFNAEPPP ELLTENYITP NPIFFTRNHL PVPNLDPDTY RLHVVGAPGG QSLSLSLDDL HNFPRYEITV TLQCAGNRRS EMTQVKEVKG LEWRTGAIST ARWAGARLCD VLAQAGHQLC ETEAHVCFEG LDSDPTGTAY GASIPLARAM DPEAEVLLAY EMNGQPLPRD HGFPVRVVVP GVVGARHVKW LGRVSVQPEE SYSHWQRRDY KGFSPSVDWE TVDFDSAPSI QELPVQSAIT EPRDGETVES GEVTIKGYAW SGGGRAVIRV DVSLDGGLTW QVAKLDGEEQ RPRKAWAWRL WQLKAPVPAG QKELNIVCKA VDDGYNVQPD TVAPIWNLRG VLSNAWHRVH VYVSP (182-545 aa encoded by BC065193)

Target Information

Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.

Human molecular genetics

González-García P,Hidalgo-Gutiérrez A,Mascaraque C,Barriocanal-Casado E,Bakkali M,Ziosi M,Abdihankyzy UB,Sánchez-Hernández S,Escames G,Prokisch H,Martín F,Quinzii CM,López LC

Wed Nov 25 00:00:00 EST 2020

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.

EMBO molecular medicine

Luna-Sánchez M,Hidalgo-Gutiérrez A,Hildebrandt TM,Chaves-Serrano J,Barriocanal-Casado E,Santos-Fandila Á,Romero M,Sayed RK,Duarte J,Prokisch H,Schuelke M,Distelmaier F,Escames G,Acuña-Castroviejo D,López LC

Sun Jan 01 00:00:00 EST 2017

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.

EMBO molecular medicine

Sun Jan 01 00:00:00 EST 2017

The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.

Antioxidants & redox signaling

Roman HB,Hirschberger LL,Krijt J,Valli A,Kožich V,Stipanuk MH

Sun Oct 20 00:00:00 EDT 2013

The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.

Antioxidants & redox signaling

Roman HB,Hirschberger LL,Krijt J,Valli A,Kožich V,Stipanuk MH

Sun Oct 20 00:00:00 EDT 2013

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.

Toxicology letters

Zhao X,Cong X,Zheng L,Xu L,Yin L,Peng J

Tue Oct 02 00:00:00 EDT 2012

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.

Toxicology letters

Zhao X,Cong X,Zheng L,Xu L,Yin L,Peng J

Tue Oct 02 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: Sulfite oxidase, mitochondrial

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Gene Aliases: SO; SUOX

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UniProt ID: (Human) P51687, (Mouse) Q8R086, (Rat) Q07116

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Entrez Gene ID: (Human) 6821, (Mouse) 211389, (Rat) 81805

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Function(s)

sulfite oxidase activity heme binding molybdenum ion binding molybdopterin cofactor binding oxidoreductase activity metal ion binding electron carrier activity oxidoreductase reductase metabolite interconversion enzyme

Process(es)

response to nutrient nitrate assimilation sulfide oxidation, using sulfide:quinone oxidoreductase oxidation-reduction process sulfur compound metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SUOX Polyclonal Antibody

SUOX Antibody (15075-1-AP) in ICC/IF

Product Details

15075-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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