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SV40 T-Antigen Antibody (PA5-112037) in ICC/IF
Immunofluorescent analysis of SV40 T-Antigen in 293T cells; (Red: cytoskeleton; Green: SV40 T-antigen stain). Sample was treated with 4% paraformaldehyde, incubated with polyclonal antibody (Product # PA5-112037) at a dilution of 1:500, followed by phalloidin (red) using a dilution of 1:100.
Product Details
PA5-112037
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of SV40 Large T antigen. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2866773
Target Information
The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: simian vacuolating virus 40; simian virus; Simian virus 40; SV40 T-antigen; sv40 virus large t antigen
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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