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Product Details
24677-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SYNJ1 Fusion Protein Ag20364 (856-1125 aa encoded by BC136603)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PVVALIDID IFEVEAEERQ NIYKEVIAVQ GPPDGTVLVS IKSSLPENNF FDDALIDELL QQFASFGEVI LIRFVEDKMW VTFLEGSSAL NVLSLNGKEL LNRTITIALK SPDWIKNLEE EMSLEKISIA LPSSTSSTLL GEDAEVAADF DMEGDVDDYS AEVEELLPQH LQPSSSSGLG TSPSSSPRTS PCQSPTISEG PVPSLPIRPS RAPSRTPGPP SAQSSPIDAQ PATPLPQKDP AQPLEPKRPP PPRPVAPPTR PAPPQRPPPP S (856-1125 aa encoded by BC136603)
Target Information
Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: inositol 5'-phosphatase (synaptojanin 1); inositol polyphosphate-5-phosphatase G; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1; Synaptojanin-1; synaptojanin-1, polyphosphoinositide phosphatase
Gene Aliases: A930006D20Rik; AA675315; INPP5G; KIAA0910; mKIAA0910; PARK20; SYNJ1
UniProt ID: (Human) O43426
Entrez Gene ID: (Human) 8867, (Mouse) 104015
nucleotide binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
protein binding
protein C-terminus binding
SH3 domain binding
protein complex binding
phosphatase
phosphatidylinositol biosynthetic process
neurotransmitter transport
learning
synaptic vesicle priming
synaptic vesicle uncoating
phosphatidylinositol-3-phosphate biosynthetic process
inositol phosphate metabolic process
phosphatidylinositol metabolic process
inositol phosphate dephosphorylation
phosphatidylinositol dephosphorylation
synaptic vesicle endocytosis
synaptic vesicle transport
positive regulation of endosome organization
positive regulation of gliogenesis
dephosphorylation
response to retinoic acid
response to cytokine
phosphatidylinositol-mediated signaling
positive regulation of receptor-mediated endocytosis
positive regulation of synaptic vesicle recycling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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