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Search Thermo Fisher Scientific
Positive test controls include: Mouse brain.
Immunogen sequence: KGSLSIEDTF ESISELGPLE LMGRELDLAP YGTLRKSQSA DSLNSISSVS NTFGQDFTLG QVEVSMEYDT ASHTLNVAVM QGKDLLEREE ASFESCFMRV SLLPDE
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
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Protein Aliases: synaptotagmin 12; Synaptotagmin XII; Synaptotagmin-12; Synaptotagmin12; SynaptotagminXII; Syt XII; SYT-12; SytXII
Gene Aliases: Syt12
UniProt ID: (Mouse) Q920N7
Entrez Gene ID: (Mouse) 171180
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