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Product Details
PA5-52771
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SYT12. Recombinant protein control fragment (Product #RP-90446).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2648158
Product Specific Information
Immunogen sequence: LLSLSYLPTA ERLTVVVVKA KNLIWTNDKT TADPFVKVYL LQDGRKMSKK KTAVKRDDPN PVFNEAMIFS VPAIVLQDLS LRVTVAESSS DGRGDNVGHV IIGPSASGMG TTHWNQMLAT LRRPVSMWHA V
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Synaptotagmin XII; Synaptotagmin-12; synaptotagmin-XII; Synaptotagmin12; SynaptotagminXII; Syt XII; SYT-12; SytXII
Gene Aliases: SYT11; SYT12; sytXII
UniProt ID: (Human) Q8IV01
Entrez Gene ID: (Human) 91683
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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