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Proteintech
Sestrin 2 Monoclonal Antibody (1A1A4), CoraLite® Plus 488
Product Details
CL488-66297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A1A4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: HMAEFLQTGG DPEWLLGLHR APEKLRKLSE INKLLAHRPW LITKEHIQAL LKTGEHTWSL AELIQALVLL THCHSLSSFV FGCGILPEGD ADGSPAPQAP TPPSEQSSPP SRDPLNNSGG FESARDVEAL MERMQQLQES LLRDEGTSQE EMESRFELEK SESLLVTPSA DILEPSPHPD MLCFVEDPTF GYEDFTRRGA QAPPTFRAQD YTWEDHGYSL IQRLYPEGGQ LLDEKFQAAY SLTYNTIAMH SGVDTSVLRR AIWNYIHCVF GIRYDDYDYG EVNQLLERNL KVYIKTVACY PEKTTRRMYN LFWRHFRHSE KVHVNLLLLE ARMQAALLYA LRAITRYMT
Target Information
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2
Gene Aliases: HI95; RGD1566319; SES2; SESN2; SEST2
UniProt ID: (Human) P58004
Entrez Gene ID: (Pig) 100620966, (Human) 83667, (Rat) 502988
regulation of protein phosphorylation
fatty acid beta-oxidation
autophagy
response to glucose
positive regulation of macroautophagy
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
mitochondrial DNA metabolic process
response to insulin
cellular response to oxidative stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
protein kinase B signaling
glucose import
triglyceride homeostasis
cellular response to amino acid stimulus
cellular response to leucine
reactive oxygen species metabolic process
regulation of gluconeogenesis involved in cellular glucose homeostasis
cellular oxidant detoxification
positive regulation of protein localization to nucleus
regulation of response to reactive oxygen species
negative regulation of translation in response to endoplasmic reticulum stress
negative regulation of TORC1 signaling
regulation of cAMP-dependent protein kinase activity
mitochondrion organization
glucose homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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