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Shaker Antibody (602-890) in WB
Western Blot: The whole cell lysate derived from HEK293 overepressed Shaker cell lysate separated in SDS-PAGE, transferred onto a NC membrane, then blotted by Rabbit anti Shaker antibody (Cat#602-890) at 1:500. An immunoreactive band is observed around ~73 kDa.
Product Details
602-890
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide derived from N-terminus of Shaker protein
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Positive control: Shaker over-expressed HEK293
Cellular location: Membrane.
Target Information
The assemblage of specific ion channels and receptors at synaptic sites is crucial for signaling between pre- and post-synaptic cells. DLG (Drosophila discs-large gene) is co-localized with Shaker K1 channels, which are clustered at glutamatergic synapses. DLG-Shaker interactions are required in vivo for shaker clustering at the neuromuscular junction. The channel protein Shaker which is properly synthesized, glycosylated, folded, assembled and delivered to the plasma membrane is very important for the potassium channel function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CG12348-PA; CG12348-PB; CG12348-PC; CG12348-PD; CG12348-PE; CG12348-PF; CG12348-PH; CG12348-PI; CG12348-PJ; CG12348-PK; CG12348-PL; CG12348-PM; CG12348-PQ; CG12348-PS; CG12348-PT; F-c transcription unit; minisleep; Potassium voltage-gated channel protein Shaker; Protein minisleep; Sh-PA; Sh-PB; Sh-PC; Sh-PD; Sh-PE; Sh-PF; Sh-PH; Sh-PI; Sh-PJ; Sh-PK; Sh-PL; Sh-PM; Sh-PQ; Sh-PS; Sh-PT; Shaker-downheld; unnamed protein product
Gene Aliases: BcDNA:GH03046; CG12348; CG17860; CG7640; Dmel\CG12348; Dmel_CG12348; EKO; F-c; K[[v]]1; Kv1; minisleep; mns; SH; Sha; Shw; V-I
UniProt ID: (Fruit fly) P08510
Entrez Gene ID: (Fruit fly) 32780
action potential
potassium ion transport
learning or memory
courtship behavior
proboscis extension reflex
larval locomotory behavior
detection of visible light
sleep
regulation of circadian sleep/wake cycle, sleep
positive regulation of membrane potential
positive regulation of circadian sleep/wake cycle, sleep
mating behavior, sex discrimination
behavioral response to ether
axon extension
sensory perception of taste
protein homooligomerization
regulation of synaptic activity
potassium ion transmembrane transport
cellular response to dopamine
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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