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Invitrogen
Sigma-1 Receptor Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-30372
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Zebrafish
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 8 and 223 of Human SIGMAR1
Conjugate
Form
Liquid
Concentration
1.09 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547846
Product Specific Information
Recommended positive controls: 293T.
Predicted reactivity: Mouse (94%), Rat (96%), Rhesus Monkey (100%), Bovine (97%), Guinea pig (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Aging-associated gene 8 protein; AL024364; mSigmaR1; opioid receptor, sigma 1; RP23 167I12.6; SIG 1R; SIG-1R; sigma 1 receptor variant SR-1D; Sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; Sigma-1 Receptor; sigma1 receptor; Sigma1-receptor; sigma1R; SR BP; SR-BP; SR31747 binding protein 1; SR31747-binding protein
Gene Aliases: AAG8; ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SIGMAR1; SR-BP; SR-BP1; SRBP; zgc:56378
UniProt ID: (Human) Q99720, (Mouse) O55242, (Zebrafish) Q7ZWG9
Entrez Gene ID: (Human) 10280, (Mouse) 18391, (Zebrafish) 393952
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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