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Sir2 (silent information regulator 2) protein plays a crucial role in regulating the life span of C. elegans by means of caloric restricion. Overexpression of the protein can extend the life span, and is, thus, a regulator of longevity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NAD-dependent protein deacetylase sir-2.1; Protein sir-2.1; Regulatory protein SIR2 homolog 1
Gene Aliases: CELE_R11A8.4; R11A8.4; sir-2.1
UniProt ID: (C. elegans) Q21921
Entrez Gene ID: (C. elegans) 177924
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