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Product Details
PA5-97200
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of human SST (NP_0010391)
Conjugate
Form
Liquid
Concentration
2.47 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2809002
Product Specific Information
Immunogen sequence: TGAPSDPRLR QFLQKSLAAA AGKQELAKYF LAELLSEPNQ TENDALEPED LSQAAEQDEM RLELQRSANS NPAMAPRERK AGCKNFFWKT FTSC
Positive Samples: HeLa, SW620, MCF7, Mouse intestine, Rat stomach
Target Information
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Growth hormone release-inhibiting factor; prepro-somatostatin; preprosomatostatin; Somatostatin; somatostatin 28; somatostatin-14; somatostatin-28; somatotropin release-inhibiting factor; SRIF
Gene Aliases: SMST; SOM; SRIF; SS; SS-14; SS-28; SST
UniProt ID: (Human) P61278, (Mouse) P60041, (Rat) P60042
Entrez Gene ID: (Human) 6750, (Mouse) 20604, (Rat) 24797
hyperosmotic response
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
cell-cell signaling
chemical synaptic transmission
response to nutrient
digestion
negative regulation of cell proliferation
hormone-mediated apoptotic signaling pathway
response to heat
response to acidic pH
regulation of cell migration
response to drug
response to amino acid
response to steroid hormone
response to organonitrogen compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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