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Synaptojanin 1 Antibody (PA5-115992) in ICC/IF
Immunocytochemistry analysis of Synaptojanin 1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115992). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Gree... View More
Product Details
PA5-115992
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SYNJ1(Accession O43426), corresponding to amino acid residues T1048-D1098.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900626
Product Specific Information
Antibody detects endogenous levels of total Synaptojanin.
Target Information
Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inositol 5'-phosphatase (synaptojanin 1); inositol polyphosphate-5-phosphatase G; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1; Synaptojanin-1; synaptojanin-1, polyphosphoinositide phosphatase
Gene Aliases: A930006D20Rik; AA675315; INPP5G; KIAA0910; mKIAA0910; PARK20; SYNJ1
UniProt ID: (Human) O43426, (Rat) Q62910
Entrez Gene ID: (Human) 8867, (Rat) 85238, (Mouse) 104015
nucleotide binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
nucleic acid binding
protein binding
protein C-terminus binding
SH3 domain binding
protein complex binding
phosphoric ester hydrolase activity
phosphatase
phosphatidylinositol biosynthetic process
neurotransmitter transport
learning
synaptic vesicle priming
synaptic vesicle uncoating
phosphatidylinositol-3-phosphate biosynthetic process
inositol phosphate metabolic process
phosphatidylinositol metabolic process
inositol phosphate dephosphorylation
phosphatidylinositol dephosphorylation
synaptic vesicle endocytosis
synaptic vesicle transport
positive regulation of endosome organization
brain development
positive regulation of gliogenesis
response to retinoic acid
response to cytokine
positive regulation of receptor-mediated endocytosis
dephosphorylation
phosphatidylinositol-mediated signaling
positive regulation of synaptic vesicle recycling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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