Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
Synaptotagmin-4 Polyclonal Antibody
Product Details
12642-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synaptotagmin-4 Fusion Protein Ag3338 (86-425 aa encoded by BC036538)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AVPKNSLHL DLEKRDLNGN FPKTNLKPGS PSDLENATPK LFLEGEKESV SPESLKSSTS LTSEEKQEKL GTLFFSLEYN FERKAFVVNI KEARGLPAMD EQSMTSDPYI KMTILPEKKH KVKTRVLRKT LDPAFDETFT FYGIPYTQIQ ELALHFTILS FDRFSRDDII GEVLIPLSGI ELSEGKMLMN REIIKRNVRK SSGRGELLIS LCYQSTTNTL TVVVLKARHL PKSDVSGLSD PYVKVNLYHA KKRISKKKTH VKKCTPNAVF NELFVFDIPC EGLEDISVEF LVLDSERGSR NEVIGQLVLG AAAEGTGGEH WKEICDYPRR QIAKWHVLCD G (86-425 aa encoded by BC036538)
Target Information
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: synaptotagmin 4; Synaptotagmin IV; Synaptotagmin-4; Synaptotagmin4; SytIV
Gene Aliases: HsT1192; KIAA1342; Syt3; SYT4; SytIV
UniProt ID: (Human) Q9H2B2, (Rat) P50232, (Mouse) P40749
Entrez Gene ID: (Human) 6860, (Rat) 64440, (Mouse) 20983
vesicle fusion
brain development
regulation of calcium ion-dependent exocytosis
negative regulation of vesicle fusion
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of dendrite extension
neurotransmitter secretion
calcium ion regulated exocytosis
negative regulation of calcium ion-dependent exocytosis
exocytosis
synaptic vesicle exocytosis
synaptic vesicle transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support