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Product Details
PA5-96781
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 38-190 of human SYT4 (NP_0658341)
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808583
Product Specific Information
Immunogen sequence: CQRKSSKSNK TPPYKFVHVL KGVDIYPENL NSKKKFGADD KNEVKNKPAV PKNSLHLDLE KRDLNGNFPK TNLKPGSPSD LENATPKLFL EGEKESVSPE SLKSSTSLTS EEKQEKLGTL FFSLEYNFER KAFVVNIKEA RGLPAMDEQS MTS; Positive Samples: SH-SY5Y, NIH/3T3, Mouse brain, Mouse spinal cord, Mouse eye, Rat brain; Cellular Location: Cytoplasmic vesicle, Single-pass membrane protein, secretory vesicle, synaptic vesicle membrane
Target Information
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: synaptotagmin 4; Synaptotagmin IV; Synaptotagmin-4; Synaptotagmin4; SytIV
Gene Aliases: HsT1192; KIAA1342; Syt3; SYT4; SytIV
UniProt ID: (Human) Q9H2B2, (Rat) P50232, (Mouse) P40749
Entrez Gene ID: (Human) 6860, (Rat) 64440, (Mouse) 20983
vesicle fusion
brain development
regulation of calcium ion-dependent exocytosis
negative regulation of vesicle fusion
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of dendrite extension
neurotransmitter secretion
calcium ion regulated exocytosis
negative regulation of calcium ion-dependent exocytosis
exocytosis
synaptic vesicle exocytosis
synaptic vesicle transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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