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Invitrogen
Synaptotagmin 7 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-52998
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Synaptotagmin 7. Recombinant protein control fragment (Product #RP-89955).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2648126
Product Specific Information
Immunogen sequence: NSLETVGTPD SGRGRSEKKA IKLPAGGKAV NTAPVPGQTP HDESDRRTEP RSSVSDLVNS LTSEMLMLSP GSEEDEAHEG CSRENLGRIQ FSVGYNFQES TLTVKIMKAQ ELPAKDFSGT SDPFVKIYLL P
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IPCA-7; Prostate cancer-associated protein 7; Synaptotagmin VII; Synaptotagmin-7; SYT-7; SytVII
Gene Aliases: IPCA-7; IPCA7; PCANAP7; SYT-VII; SYT7; SYTVII
UniProt ID: (Human) O43581
Entrez Gene ID: (Human) 9066
plasma membrane repair
vesicle fusion
phagocytosis
regulation of calcium ion-dependent exocytosis
synaptic vesicle recycling
positive regulation of calcium ion-dependent exocytosis
regulation of bone remodeling
calcium ion-regulated exocytosis of neurotransmitter
regulation of phagocytosis
regulation of insulin secretion
regulation of glucagon secretion
vesicle-mediated cholesterol transport
phagosome-lysosome fusion
short-term synaptic potentiation
calcium ion regulated lysosome exocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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