Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: MRDRLPDLTA CRKNDDGDTV VVVEKDHFMD DFFHQVEEIR NSIDKITQYV EEVKKNHSII LSAPNPEGKI KEELEDLNKE IKKTANKIRA KLKAIEQSFD QDESGNRTSV DLRIRRTQHS VLSRKFVEAM AEYNEAQTLF RERSKGRIQR QLEITGRTTT DDELEEMLES GKPSIFTSDI ISDSQITRQA LNEIESRHKD IMKLETSIRE LHEMFMDMAM FVETQGEMIN NIERNVMNAT DYVEHAKEET KKAIKYQSKA RRKL; Positive Samples: K-562, DU145, SKOV3, A-549, Mouse heart, Mouse testis, Rat liver, Rat heart, Rat testis; Cellular Location: Membrane, Single-pass type IV membrane protein
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Epimorphin; MGC51014; Syntaxin-2
Gene Aliases: AW538950; EPIM; EPM; G1-536-1; repro34; STX2; STX2A; STX2B; STX2C; Syn-2
UniProt ID: (Human) P32856, (Rat) P50279
Entrez Gene ID: (Human) 2054, (Mouse) 13852, (Rat) 25130
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