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Product Details
13839-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAC1 Fusion Protein Ag4790 (20-129 aa encoded by BC018047)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to TAC1.
Immunogen sequence: EEIGANDDL NYWSDWYDSD QIKEELPEPF EHLLQRIARR PKPQQFFGLM GKRDADSSIE KQVALLKALY GHGQISHKRH KTDSFVGLMG KRALNSVAYE RSAMQNYERR R (20-129 aa encoded by BC018047)
Target Information
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; PPT; preprotachykinin; preprotachykinin A; protachykinin; Protachykinin-1; substance K; substance P; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Gene Aliases: 4930528L02Rik; Hs.2563; NK-1; NK1; NK2; NKA; NKNA; NPK; PPT-A; PPTA; SP; TAC1; TAC2
UniProt ID: (Human) P20366, (Mouse) P41539
Entrez Gene ID: (Human) 6863, (Mouse) 21333
positive regulation of acute inflammatory response
inflammatory response
positive regulation of cytosolic calcium ion concentration
tachykinin receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
insemination
long-term memory
regulation of blood pressure
associative learning
detection of abiotic stimulus
response to hormone
negative regulation of heart rate
positive regulation of epithelial cell migration
sensory perception of pain
positive regulation of synaptic transmission, cholinergic
positive regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
positive regulation of renal sodium excretion
response to morphine
positive regulation of action potential
positive regulation of ossification
positive regulation of saliva secretion
response to pain
positive regulation of lymphocyte proliferation
positive regulation of stress fiber assembly
cellular response to nerve growth factor stimulus
positive regulation of corticosterone secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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