Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Sequence of this protein is as follows: MKRVRTEQIQ MAVSCYLKRR QYVDSDGPLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY SRFHGMFLQN ASQKDVIEQL QTTQTIQDIL SNFKLRAFLD NKYVVRLQED SYNYLIRYLQ SDNNTALCKV LTLHIHLDVQ PAKRTDYQLY ASGSSSRSEN NGLEPPDMPS PILQNEAALE VLQESIKRVK DGPPSLTTIC FYAFYNTEQL LNTAEISPDS KLLAAGFDNS CIKLWSLRSK KLKSEPHQVD VSRIHLACDI LEEEV
TAF5L (TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L), also known as PAF65B, is a 589 amino acid protein that localizes to the nucleus and contains six WD repeats. Existing as a component of the PCAF histone acetylase complex, TAF5L interacts with a number of TAFs and, via this interaction, plays a role in histone acetylation and transcription initiation. Defects in the gene encoding TAF5L, which is expressed as multiple alternatively spliced isoforms, are associated with the pathogenesis of type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PAF65-beta; PCAF associated factor 65 beta; PCAF-associated factor 65 beta; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF5L; TATA box binding protein associated factor 5 like
Gene Aliases: PAF65B; TAF5L
UniProt ID: (Human) O75529
Entrez Gene ID: (Human) 27097
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support