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TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 22 kDa actin-binding protein; Actin-associated protein p27; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; sm22 alpha; SM22-alpha; Sm22alpha; Smooth muscle protein 22-alpha; Transgelin; transgelin variant 2
Gene Aliases: SM22; Sm22a; SMCC; TAGLN; TAGLN1; WS3-10; Ws310
UniProt ID: (Human) Q01995, (Mouse) P37804
Entrez Gene ID: (Human) 6876, (Mouse) 21345
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