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Immunogen sequence: EEKLSNPPAT CTPGKPSSKS QNKCKPSQGL STEENLSASI TKQPIHQKEN IIPLLVTSNS DQFLTTPDGD EKDITQDNSE LKHRSSKKD
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.
This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytomegalovirus partial fusion receptor; Transmembrane anterior posterior transformation protein 1 homolog
Gene Aliases: CMVFR; OCLSBG; TAPT1
UniProt ID: (Human) Q6NXT6
Entrez Gene ID: (Human) 202018
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