Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MSDTLTADV IGRRVEVNGE HATVRFAGVV PPVAGPWLGV EWDNPERGKH DGSHEGTVYF KCRHPTGGSF IRPNKVNFGT DFLTAIKNRY VLEDGPEEDR KEQIVTIGNK PVETIGFDSI MKQQSQLSKL QEVSLRNCAV SCAGEKGGVA EACPNIRKVD LSKNLLSSWD EVIHIADQLR HLEVLNVSEN KLKFPSGSVL TGTLSVLKVL VLNQTGITWA EVLRCVAGCP GLEELYLESN NIFISERPTD VLQTVKLLDL SSNQLIDENQ LYLIAHLPRL EQLILSDTGI SSLHFPDAGI GCKTSMFPSL KYLVVNDNQI SQWSFFNELE K (1-330 aa encoded by BC008654)
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hypoparathyroidism, growth and mental retardation, and dysmorphism; Tubulin-folding cofactor E; Tubulin-specific chaperone E
Gene Aliases: 2610206D02Rik; C530005D02Rik; HRD; KCS; KCS1; pac2; pmn; TBCE
UniProt ID: (Human) Q15813, (Rat) Q5FVQ9, (Mouse) Q8CIV8
Entrez Gene ID: (Human) 6905, (Rat) 361255, (Mouse) 70430
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